BACKGROUND & OBJECTIVE Tuberculosis is the commonest opportunistic disease in persons infected with human immunodeficiency virus (HIV). Emergence of drug resistant isolates of M. tuberculosis highlights the need for continuous monitoring of drug resistance to antituberculosis drugs. Considering the reported high prevalence of drug resistance in HIV infected tuberculosis patients, we studied the...

BACKGROUND Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. METHODS Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. RESULTS Ten (31%) of 32 culture-positive patients were resistant to at least o...

Throughout the history of mankind, infectious diseases have remained a major cause of death and disability. Although industrialized nations, such as the United States, have experienced significant reductions in infection-related mortality and morbidity since the beginning of the "antibiotic era," death and complications from infectious diseases remain a serious problem for older persons. Pneumo...

A problem arises when a plant, animal, or person becomes infected with a disease-causing bacterium that harbors antibiotic resistance to the drug that would be the most suitable treatment for that infection. In many cases, other drugs, to which the bacteria is not resistant, can be used to combat the infection. However, in cases where our choices of effective drugs are limited, or the bacterium...

Anti-TB drugs for children: Aetiotropic therapy is used the treatment of tuberculosis (TB) in children, as well adult patients. Anti-tuberculosis (anti-TB drugs) are divided into 3 lines, taking account drug sensitivity Mycobacterium (MBT). First-line anti-TBdrugs (basic) to treat TB caused by drug-susceptible MBT. Second- and third-line (reserve) recommended MBT-induced multidrug-resistant (MD...

Introduction: Globally, drug-resistant tuberculosis (TB) still has a high number of cases. Pregnant women are one the high-risk populations for TB infection, especially multidrug resistance (MDR)/Rifampicin (RR) TB. Physiological differences in pregnant and safety fetus make drug treatment challenging. Case: A 20-year-old woman was 22 weeks while undergoing third month late phase short-regimen....