نتایج جستجو برای: drug release profile

تعداد نتایج: 973228  

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 2015
m. christe sonia mary s. sasikumar

in the present study, floating drug delivery beads (fdds) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. in order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the consti...

AS Kiran BS Ashok Kumar D Sheshadri Shaker KV Satish N Narayana Swamy N Suresh,

      An oral suspension could a suitable dosage form for the geriatric patients. The calcium alginate coated ion exchange resinate of propranolol hydrochloride were prepared using Amberlite IR-120 by solvent evaporation. Microcapsules of propranolol hydrochloride resinate were prepared by solvent evaporation technique,the suspensions were prepared by using deionised water as the vehicle. Methy...

Resistance to aspirin and its cytotoxicity significantly limits its therapeutic applications. Nano-liposomal encapsulation of aspirin can reduce its cytotoxicity. In this study, aspirin encapsulated nano-liposomes (AS-NL) was prepared and its performance in drug delivery and cytotoxicity was evaluated. The effects of two independent variables including: number of freeze/thawing cycles and conce...

Journal: :Journal of Drug Delivery and Therapeutics 2023

This research focused on preparing a ketoconazole-infused silk fibroin hydrogel to enhance patient compliance, leveraging the hydrogel's biocompatibility and biodegradability. The process used 50% (v/v) ethanol, propanol, or glycerol solution treated with 2% (w/v) at 37°C. use of quickened gelation process. structure was analyzed via SEM, UV-VIS spectrometry evaluate encapsulation efficiency ke...

2014
Susan Hua

BACKGROUND The purpose of this study was to determine the most appropriate dialysis equilibrium method to assess liposomal gel formulations containing hydrophobic drugs, to give the most accurate indication of drug release. METHODS Loperamide hydrochloride-encapsulated liposomes, composed of L-α-phosphatidylcholine and cholesterol (molar ratio of 2:1), were prepared according to the method of...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007
Uttam Mandal Veeran Gowda Animesh Ghosh Senthamil Selvan Sam Solomon Tapan Kumar Pal

The aim of the current study was to design an oral sustained release matrix tablet of metformin HCl and to optimize the drug release profile using response surface methodology. Tablets were prepared by non-aqueous wet granulation method using HPMC K 15M as matrix forming polymer. A central composite design for 2 factors at 3 levels each was employed to systematically optimize drug release profi...

Journal: :jundishapur journal of natural pharmaceutical products 0
eskandar moghimipour nanotechnology research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of pharmaceutics, faculty of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran anayatollah salami nanotechnology research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of pharmaceutics, faculty of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; corresponding author: anayatollah salami, department of pharmaceutics, faculty of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-6133738381 mahsa monjezi department of pharmaceutics, faculty of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

materials and methods liposomes were prepared by thin film method using soya lecithin and cholesterol. physicochemical characteristics of the liposomes such as, particle size, drug encapsulation efficiency were determined. also, drug release and in vitro skin permeability through rat skin were evaluated using franz diffusion cells. results the results showed that the maximum drug encapsulation ...

Bolai Paul, Mohd Javed Qureshi Senthil Adimoolam

Amoxicillin (α-amino-p-hydroxybenzyl-penicillin) is a semi-synthetic, orally absorbed and widely prescribed β-lactam antibiotic. It is now widely used for eradication of gastric Helicobacter pylori infection combined with a second antibiotic and an acid‐suppressing agent despite its short elimination half-life of one hour. The purpose of this study was to develop and evaluate amoxicillin loaded...

2014
Shivani Patel Mihir Patel

The present research concerns the formulation and evaluation of sustained release pellets filled capsule of opioid analgesic, Tramadol HCl. Development of sustained release dosage form is to maintain therapeutic blood levels of the drug for extended period of time. Sustained release formulation provides uniform concentration at absorption site, maintains plasma concentration within a therapeuti...

Journal: :Acta pharmaceutica 2005
Rassoul Dinarvand Sanaz Mahmoodi Effat Farboud Massoud Salehi Fatemeh Atyabi

In this study, gelatin microspheres containing lactic acid were prepared by the polymerization technique using glutaraldehyde as the cross-linking agent. Dried microspheres were loaded by immersing them in an aqueous solution of lactic acid. In order to prepare microspheres with an appropriate drug release profile, the effect of time of cross-linking and the amount of cross-linking agent on the...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید