Corticosteroids have been the mainstay of uveitis therapy. When intraocular inflammation is unresponsive to steroids, or steroid related side effects become a concern, steroid-sparing medications may be administered which can be classified into immunosuppressive and immunomodulatory agents. Uveitis treatment can be delivered systemically, topically, periocularly or intraocularly. All of the abo...

OBJECTIVE According to the basic role of drug side effects in selection of an appropriate drug, patient compliance and the quality of life in epileptic patients, and forasmuch as new drugs with unknown side effect have been introduced, necessity of this research is explained. This study was conducted to evaluate the incidence and clinical characteristics of anti epileptic drug (AED) related adv...

Intrahepatic cholestatic hepatitis is a rare but therapy-limiting side effect of antiarrhythmic drugs, in literature only few reports are related to the subscription of ajmaline [1-3]. As potential causes for development of intrahepatic cholestatic hepatitis drug-triggered autoimmune reactions as well as direct toxic effects are recently discussed. However, the mechanism of this severe hepatic ...

Abstract Background Disseminated Mycobacterium marinum infections occur rarely, in immunocompromised patients. Treatment with a prolonged multi-drug regimen exposes patients to drug–drug interactions and side effects. Case report We case of disseminated M. infection 54-year-old renal transplant, HIV-infected woman. Manifestations the were cutaneous subcutaneous nodules, mediastinal lymph nodes ...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...

ôbjective: to compare the effectiveness and safety of the methylphenidate produced in ïran (stimdate®) with its original brand (ritalin®) in children with âttention deficit hyperactivity disorder (âdhd). methods: ïn this double-blinded randomized clinical trial, 30 patients with âdhd who were 6 to 16 years old, were divided into two groups: 15 in stimdate® and 15 in ritalin® group. the two grou...

objective: to compare side effects between users of two kinds of injectable contraceptives (depo-medroxy progesterone acetate and cyclofem). materials and methods: this cross-sectional descriptive study included 250 women, aged 18-40 years, using depo-medroxy progesterone acetate (dmpa) or cyclofem. the volunteers were examined six months after using contraceptive, and they were asked about fol...

conclusions administration of aeds in general and levetiracetam in particular should be based on attention to pharmacokinetic behavior in terms of monotherapy or polypharmacy. case presentation two cases were studied, one patient was a 32-year-old male and the other was a 14-year-old female. the key words relevant to search topics were surveyed using pubmed (united states national library of me...

the administration of b-interferon is a recognized treatment for multiple sclerosis. the frequency of side effects is an important factor in drug or product selection. in this study, the side effects of three available b-interferon products are compared in 122 multiple sclerosis patients who were treated with b-interferon products for at least three months and had the expanded disability status...