DRUG ADDIcTIoN, especially through the use of poppy (Papaver somniferum Linn.) and hemp (Cannabis sativa Linn.), is the main concern of this paper. Although the use of these two plants in medieval Islam was extensive, yet little has been written on this timely subject by historians of medicine and pharmacology. Consulting contemporary original sources, it is my hope to sketch a history of their...

Medication errors are one of the important factors that increase fatal injuries to the patients and burden significant economic costs to the health care. An appropriate medical history could reduce errors related to omission of the previous drugs at the time of hospitalization. The aim of this study, as first one in Iran, was evaluating the discrepancies between medication histories obtained by...

Medication errors are one of the important factors that increase fatal injuries to the patients and burden significant economic costs to the health care. An appropriate medical history could reduce errors related to omission of the previous drugs at the time of hospitalization. The aim of this study, as first one in Iran, was evaluating the discrepancies between medication histories obtained by...

I. History of medicines regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 II. Why regulating drugs? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 III. What is medicines regulation? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 IV. Drug registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Some cancers like melanoma and pancreatic and ovarian cancers, for example, commonly display resistance to chemotherapy, and this is the major obstacle to a better prognosis of patients. Frequently, literature presents studies in monolayer cell cultures, 3D cell cultures or in vivo studies, but rarely the same work compares results of drug resistance in different models. Several of these works ...

Pharmacology started to develop into a real quantitative science in 1909, when A.V. Hill derived the Langmuir equation in the course of his studies on nicotine and curare. A history of the developments since then shows both brilliant insights and missed opportunities. It also shows that much remains to be done. There is still no mathematical description that can describe quantitatively the acti...

This article examines the history of efforts to add prescription drug coverage to the Medicare program. It identifies several important patterns in policymaking over four decades. First, prescription drug coverage has usually been tied to the fate of broader proposals for Medicare reform. Second, action has been hampered by divided government, federal budget deficits, and ideological conflict b...

The review article is devoted to the history of creation, biological effects and clinical application entomological drug Adenoprosin. data experimental studies are presented, indicating a high activity drug, mechanisms its therapeutic action described. pharmacological Adenoprosin were analyzed, which ensure efficacy good tolerability. pathogenetic validity appointment in patients with chronic p...

BACKGROUND Although previous studies have identified high levels of drug-related harm in Thailand, little is known about illicit drug overdose experiences among Thai drug users. We sought to investigate non-fatal overdose experiences and responses to overdose among a community-recruited sample of injection drug users (IDU) in Bangkok, Thailand. METHODS Data for these analyses came from IDU pa...

BACKGROUND Despite drug-related hypersensitivity reactions are an important health problem, epidemiologic data on drug allergy and hypersensitivity are limited, and studies including diagnostic work-up are scarce. The aim of this study was to determine the actual frequency of immediate type drug hypersensitivity using diagnostic tests in school children with parent-reported drug allergies. ME...