Background. Antiresorptive drug-related osteonecrosis of the jaw (ADRONJ) is a serious complication cancer patients or osteoporosis, under treatment with antiresorptive drugs. At present, there no scientific evidence consensus on most appropriate approach depending stages ADRONJ. Objective. To assess effectiveness different therapeutic options in Search methods. The following electronic databas...

This study evaluated the relationships among copeptin, ischemia-modified albumin (IMA), and extent of myocardial injury in patients with acute carbon monoxide poisoning (ACOP). A total of 110 patients with different degrees of ACOP were selected as the poisoning group, and 30 healthy individuals as the control group. The levels of troponin I (cTnI), IMA, and copeptin were detected. Based on the...

aortic aneurysm is a rare but potentially lethal complication during pregnancy. in this article we described a 30-year-old woman with a large size descending aorta aneurysm (11 cm in length and 5.6 cm in its greatest diameter), who had two term uncomplicated pregnancies. the patient received prophylactic ß-blocker drug during her second pregnancy. both pregnancies were terminated by caesarean s...

PURPOSE The purpose of this study was to evaluate the efficacy and safety of adjunctive retigabine/ezogabine (RTG/EZG) therapy in Asian adults with partial-onset seizures. METHODS A Phase III, randomized, double-blind, placebo-controlled, parallel-group study was conducted at 26 centers in Asia. Eligible patients were randomized in a 1:1:1 ratio to receive RTG/EZG 600mg/day (200mg 3 times dai...

BACKGROUND Illicit drug use has become an increasing public health and social concern in the past decades worldwide. Intravenous injection has an elevated risk of infection. Needle embolism is a rare complication of intravenous drug users, Retained broken needles can lead to local complications, such as infection, but they also have the potential to embolize to heart or lung, and lead to seriou...

Patience who suffered from menstrual pain disease is generally prescribed the non-steroidal anti-inflammatory drug (NSAIDs). Monorrhagia or another blood disorder & some gynecological disorder, which impairs body function and acts as an economic burden. Due to respective use of ACE by oral route, it may cause GI complication such bleeding, pain, perforation, abdominal swelling. To decrease ...

Plasma is used to correct coagulopathies, but not all coagulation abnormalities are clinically significant enough to require correction before an invasive procedure. We report an 82-year-old female who, in response to a mildly prolonged INR of unknown etiology, was unnecessarily transfused with plasma in advance of elective surgery. The patient suffered a moderately severe transfusion reaction,...

Introduction. Antitumor necrosis factor (TNF) alpha agents are commonly used biologic therapies for a wide variety of rheumatic and inflammatory diseases. Here, we present a case of hemorrhagic pericarditis as a consequence of infliximab and review the literature on pericardial complications stemming from this drug class. Methods. For the literature review, search terms using versions of antitu...

Some otolaryngologists administer topical phenylephrine for bleeding control in adenoidectomy surgery. Absorption of this drug from surgical site can lead to increase in blood pressure due to vasoconstriction and then bradycardia related to baroreceptore reflex.  Our case was an intraoperative arrest of a 9-yrs-old girl related to administration of topical phenylephrine during adenoidectomy how...

Mastoiditis is a common complication of acute otitis media. It in younger age compared to adulthood. occurs when an media infection spread directly involve the bone mastoid air cell causing osteitis. Cholesteatoma can contribute development mastoiditis. This typically leads breakdown some fine bony trabeculae cells producing coalescent mastoiditis with emphyema antrum. The treatment for intrave...