1.1 Mechanical ventilation Mechanical ventilation is often employed to replace spontaneous breathing of patients under general anesthesia. Even after operation, the patient still needs ventilation support until the respiratory muscles regain full function. A ventilator delivers a certain amount of air flow through a facial mask or tracheal tube to the patient whose respiratory system fails to f...

PURPOSE Four-dimensional dynamic-ventilation CT imaging demonstrates continuous movement of the lung. The aim of this study was to assess the correlation between interlobar synchrony in lung density and spirometric values in COPD patients and smokers, by measuring the continuous changes in lung density during respiration on the dynamic-ventilation CT. MATERIALS AND METHODS Thirty-two smokers,...

Accurate CFD simulation of coupled outdoor wind flow and indoor air flow is essential for the design and evaluation of natural cross-ventilation strategies for buildings. It is widely recognized that CFD simulations can be very sensitive to the large number of computational parameters that have to be set by the user. Therefore, detailed and generic sensitivity analyses of the impact of these pa...

patients and methods a cross-sectional study was conducted at icus of imam-reza and vali-asr hospitals, birjand, iran. sampling was done through a census in which 53 icu nurses participated. descriptive statistics, kolmogorov-smirnov test, mann-whitney u tests and kendall's correlation coefficient were used to analyze the data. results a total of 53 nurses participated in this study. most of th...

OBJECTIVES Mechanical ventilation is injurious to the lung. Use of lung-protective strategies may complicate patient management, motivating a search for better lung-replacement approaches. We investigated the ability of a novel extracorporeal venovenous CO2 removal device to reduce minute ventilation while maintaining normocarbia. DESIGN Prospective animal study. SETTING Government laborato...

In patients with Late-Onset Pompe Disease (LOPD), progressive respiratory muscle involvement leads to reduced pulmonary function, with respiratory failure the most common cause of mortality. Early disease manifestations include sleep-disordered breathing, which can be treated with non-invasive ventilation; however, progressive diurnal deficits can require invasive ventilation. To determine if p...