The present paper reports evidence of an immunological relationship between one variety or type of the yeast Saccharomyces cerevisi~e and the Type II variety of Diplococcus pn,umoni~e (Pneumococcus). The immunological interrelationships among the different yeasts have never been well established, but it is certain that all of the yeasts included by the species term Saccharomyces cerevisi~ are n...

Oral midazolam is a frequently used sedative in pediatric dentistry. Although an oral form of midazolam is now commercially available, some practitioners continue to use the IV midazolam as an oral medication. If the injectible form of midazolam is administered orally, its bitter taste requires the use of a flavoring agent. Grapefruit juice is contraindicated for this purpose as it inhibits cyt...

Traditional newborn dried blood spot screening (NDBS) has expanded in recent years to include upwards of 50 different conditions in many states. Once the screening tests are complete, the residual blood specimens (RBSs) that remain are most often available for quality assurance and public health research. The articles by Botkin et al1 and Bombard et al2 contained in this issue of Pediatrics inv...

One hundred per cent apple, orange and grapefruit juices were analysed for ascorbic acid (AA) content, total polyphenolic content (TPC), other parameters: titratable acids (TA), malic (MA), citric (CA), volatile (VA), soluble solids (SS), density, the of free amino as formol number (FN). Some apple on Czech market contain added vitamin C, AA such (268–632 mg L–1) is several times higher than th...

Easy-to-use naloxone formulations are needed to help address the opioid overdose epidemic. The pharmacokinetics of i.v., i.m., and a new i.n. naloxone formulation (2 mg) were compared in six healthy volunteers. Relative to i.m. naloxone, geometric mean (90% confidence interval [CI]) absolute bioavailability of i.n. naloxone was modestly lower (55%; 90% CI, 43-70% vs. 41%; 90% CI, 27-62%), where...