It is impossible to wear clothes without transmitting social signals. Every costume tells a story, often a very subtle one, about its wearer. A couple of years ago, I visited the Mayo Clinic in Rochester, Minnesota, and was surprised to see that most physicians still wore suits, while here in Chapel Hill where I work, I am only one of a handful to do so.* I wear a suit because I feel that it ma...

A 45 years old female on allopurinol for 3 months presented with itching, rash, facial oedema and eosinophilia with hepatic and renal dysfunction. Skin biopsy revealed interface dermatitis, suggesting the diagnosis of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome.

Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a rare and severe drug-induced hypersensitivity syndrome characterized by haematological abnormalities (hypereosinophilia and/or mononucleosis) and multiorgan involvement. Renal failure has been rarely described. We report the case of a 77-year-old female with sulphasalazine-induced DRESS syndrome who improved rapidly on cort...

A relatively new drug used in the treatment of osteoporosis, strontium ranelate has been associated with several side effects, including increased relative risk of venous thromboembolism (including pulmonary embolism), transient increases in creatine kinase levels, mild gastrointestinal, nervous system and muscular disorders, and drug-induced hypersensitivity syndrome, also called DRESS syndrom...

Hepatitis A virus (HAV) infections occur predominantly in children, and are usually self-limiting. However, 75-95% of the infections in adults are symptomatic (mostly with jaundice), with the illness symptoms usually persisting for a few weeks. Atypical manifestations include relapsing hepatitis, prolonged cholestasis, and complications involving renal injury. Drug rash with eosinophilia and sy...

prompt diagnosis is essential to improve the prognosis. Sulfasalazine is one of the essential drugs used for the treatment of IBD as well as rheumatic diseases such as rheumatoid arthritis and spondyloarthropathies. While many studies have described experiences of sulfasalazine-induced DRESS in rheumatic diseases, few such reports have examined in relation to IBD. We herein describe a case of D...

Background Drug reaction with eosinophilia and systemic symptom (DRESS) is a severe drug-induced cutaneous reaction with visceral involvement and blood abnormalities associated with reactivations of herpes-virus family i.e., EBV, HHV-6, HHV-7 and CMV. Recently, we demonstrated that the immune response in DRESS, previously thought to be directed only against drug components, is also mediated by ...

Methods We examined cases of DRESS syndrome which were reported to our pharmacovigilance centre 2008-2013 and cases reported in the literature during the same period for which CRP and/or PCT were available. Peak values were recorded whenever possible. The extent of CRP and PCT elevation in cases where DRESS syndrome was not due to antibiotics was also studied as these cases were less likely to ...

Introduction / objectives Nurse uniforms can act as a reservoir of infections, with the areas around the pockets, cuffs and aprons the most contaminated. The aim of this study is compare the contamination of Standard nurse’s uniform consisted of a dress, pinafore apron with the “scrub dress” type of uniform, as well as to measure the influence of the number of shifts as uniform was used in its ...

Intraperitoneal vancomycin is used for empiric treatment of peritoneal dialysis peritonitis. It is dosed intermittently and a high systemic concentration is often achieved. Despite this, there are very few reports of systemic toxicity from intraperitoneal vancomycin. We report the course of a patient who developed a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome after th...