The adult female rats hoard large quantities of food during proestrus and continue hoarding if ovariectomised at proestrus (Group I). The hoarding score is lowest in diestrus and continue to remain low if ovariectomised during this phase (Group II). The scores in Group I and Group II are reversed in intracerebral administration of Progesterone and Estradiol Benzoate respectively into preoptic a...

This paper introduces a novel top-down approach to geospatially identify and distinguish areas of mixed use from predominantly residential areas within urban agglomerations. Under the framework of the World Bank’s Central American Country Disaster Risk Profiles (CDRP) initiative, a disaggregated property stock exposure model has been developed as one of the key elements for disaster risk and lo...

NOONAN, M. AND M. B. KRJSTAL. Effects (~fmedial preoptic lesions on placentophaRia and on the onset ofmaternal be­ havior in the rat. PHYSJOL. BEHAV. 22(6) 1197-1202, 1979.-Lesions of the medial preoptic area (MPO) were produced through permanently indwelling electrodes 24 hr prior to parturition in pregnant rats, or 24 hr prior to donor-placenta presentation in virgin rats determined in a pret...

Preoptic area has neurons which change their firing rate along with spontaneous alterations of the cortical EEG between synchronization and desynchronization. The cortical EEG synchronization and desynchronization could be induced by stimulation of the caudal and the rostral brain stem respectively. This study was aimed at finding out whether stimulation of the brain stem structures produce the...

The changes in brain temperature and sleep-wakefulness were studied in rats during their exposure to different ambient temperatures of 18 degrees C, 24 degrees C and 30 degrees C, before and after N-methyl D-aspartic acid lesion of the medial preoptic area. The medial preoptic area lesion produced a decrease in sleep, and increase in brain temperature except at 30 degrees C. Increase and decrea...

During spring sheep do not normally ovulate but exposure to a ram can induce ovulation. In some ewes an LH surge is induced immediately after exposure to a ram thus raising questions about the control of this precocious LH surge. Our first aim was to determine the plasma concentrations of oestradiol (E2) E2 in anoestrous ewes before and after the "ram effect" in ewes that had a "precocious" LH ...

Maternal behavior is dynamic and highly sensitive to experiential and contextual factors. In this review, this plasticity will be explored, with a focus on how experiences of females occurring from the time of fetal development through to adulthood impact maternal behavior and the maternal brain. Variation in postpartum maternal behavior is dependent on estrogen sensitivity within the medial pr...

The objective of the study was to introduce the availability of bold imaging facility at Aga Khan University Hospital Karachi for the first time in Pakistan and also to review the practical application and advantages of functional magnetic resonance imaging (fMRI) and blood oxygen level dependant (BOLD) Imaging Procedures. The study was conducted at Aga Khan University Hospital, Karachi from Au...

Injection of chemicals into the brain has been considered as an important technique to study various functions of the brain. In these studies, as a rule, only one bilateral injection is given in one animal. This study was undertaken to evaluate the quality of the body temperature data obtained after first and second injections of methoxamine and artificial cerebrospinal fluid into the medial pr...

Within the surgical treatment of glioma, extended survival is predicated upon extent of resection which is limited by proximity and/or invasion of eloquent structures. Diffusion tensor imaging (DTI) tractography is a very useful tool for guiding supramaximal surgical resection while preserving eloquence. Although gliomas can vary significantly in size, shape, and invasion of functionally signif...