Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Portugal In order to ensure the safe usage of new radiopharmaceuticals in Positron Emission Tomography (PET), it is necessary to quantify the doses delivered to the organs and tissues within the patients’ bodies. A framework that allows estimating the dose delivered by PET has been established by the MIRD Committee ...

We compared the implant quality of intraoperatively built custom-linked (IBCL) seeds with loose seeds in permanent prostate brachytherapy. Between June 2012 and January 2015, 64 consecutive prostate cancer patients underwent brachytherapy with IBCL seeds (n = 32) or loose seeds (n = 32). All the patients were treated with 144 Gy of brachytherapy alone. Brachytherapy was performed using a dynami...

Seven years of experience in compensator intensity-modulated radiotherapy (IMRT) clinical implementation are presented. An inverse planning dose optimization algorithm was used to generate intensity modulation maps, which were delivered via either the compensator or segmental multileaf collimator (MLC) IMRT techniques. The in-house developed compensator-IMRT technique is presented with the focu...

Abstract Introduction: This is the second of two papers giving an overview use Monte-Carlo techniques for radiotherapy applications. Methods: The first paper gave introduction and introduced some codes that are available to user wishing model different aspects treatment. It also aims serve as a useful companion curated collection on have been published in this journal. Results Conclusions: focu...

Medical dosimetry education occupies a specialized branch of allied health higher education. Noted international shortages of health care workers, reduced university funding, limitations on faculty staffing, trends in learner attrition, and increased enrollment of nontraditional students force medical dosimetry educational leadership to reevaluate current admission practices. Program officials ...

*Corresponding author: Dr. Tayyeb Allahverdi Pourfallah, Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran. Fax: +98 21 88973653 E-mail: [email protected] Background: Polymer gel dosimetry is still the only dosimetry method for direct measuring of threedimensional dose distributions. MRI Polymer gel dosimeters are tissue equi...

Integrated systems combining functional (single-photon emission computed tomography; SPECT) imaging with anatomic (computed tomography; CT) imaging have the potential to greatly improve the accuracy of dose estimation in radionuclide therapy. In this article, we present the methodology for highly patient-specific tumor dosimetry by utilizing such a system and apply it to a pilot study of 4 foll...

Kidney dosimetry in (177)Lu and (90)Y PRRT requires 3 to 6 whole-body/SPECT scans to extrapolate the peptide kinetics, and it is considered time and resource consuming. We investigated the most adequate timing for imaging and time-activity interpolating curve, as well as the performance of a simplified dosimetry, by means of just 1-2 scans. Finally the influence of risk factors and of the pepti...

BACKGROUND Patient-specific absorbed dose calculations for molecular radiotherapy require accurate activity quantification. This is commonly derived from Single-Photon Emission Computed Tomography (SPECT) imaging using a calibration factor relating detected counts to known activity in a phantom insert. METHODS A series of phantom inserts, based on the mathematical models underlying many clini...

Significant advances have been made in recent years to improve calibration methodology and dose calculation algorithm in the fields of TL dosimetry. This process was accelerated in the past decade particularly in the Republic of Korea by the need to meet mandatory national accreditation requirements. The objective of this study is to develop a new algorithm to replace the simplistic decision tr...