The purpose of this study is to perform dosimetric validation of Monaco treatment planning system version 5.1. The Elekta VersaHD linear accelerator with high dose rate flattening filter-free photon modes and electron energies was used in this study. The dosimetric output of the new Agility head combined with the FFF photon modes warranted this investigation into the dosimetric accuracy prior t...

Abstract PURPOSE We found that cognitive function remained stable following radiotherapy with concurrent and adjuvant temozolomide (RT+TMZ) in low-grade glioma (LGG) patients evaluated prospectively up to 2 years. This study evaluates the effects of dosimetry on neurocognitive a larger group molecularly defined LGG treated (RT). METHODS A total 39 were comprehensive psychometric tests at baseli...

BACKGROUND The purpose of this study was to determine the clinical and dosimetric factors associated with acute esophagitis (AE) in lung cancer patients treated with conformal radiotherapy (RT) in Turkey. MATERIALS AND METHODS In this retrospective review 104 lung cancer patients were examined. Esophagitis grades were verified weekly during treatment, and at 1 week, and 1 and 2 months afterwa...

♦Corresponding Author: Maher Soliman, MD Oncology Department, Faculty of Medicine, Alexandria University, Alexandria 21526, Alexandria, Egypt Tel: (+2) 03-4848280 Fax: (+2) 03-4848280 E-mail: [email protected] Abstract Background: Radiation-induced lung toxicity is an important dose-limiting toxicity in lung cancer radiotherapy, for which there are no generally accepted predictive fa...

The purpose of this study was to evaluate the impact of emphysematous changes in lung on dosimetric parameters in stereotactic body radiation therapy (SBRT) for lung tumor. A total of 72 treatment plans were reviewed, and dosimetric factors [including homogeneity index (HI) and conformity index (CI)] were evaluated. Emphysematous changes in lung were observed in 43 patients (60%). Patients were...

BACKGROUND To identify dosimetric parameters associated with acute hematologic toxicity (HT) in rectal cancer patients undergoing concurrent chemotherapy and intensity-modulated pelvic radiotherapy. METHODS Ninety-three rectal cancer patients receiving concurrent capecitabine and pelvic intensity-modulated radiation therapy (IMRT) were analyzed. Pelvic bone marrow (PBM) was contoured for each...

PURPOSE A retrospective study was performed to determine any dosimetric or delivery benefits for treatment planning with intensity-modulated radiotherapy (IMRT) versus volumetric-modulated arc therapy (VMAT) for the treatment of brain neoplasms. METHODS Eighteen patients treated with modulated brain radiotherapy treatments were included in this study (primary treatment volumes of 15.3 to 374....

This report addresses uncertainties pertaining to brachytherapy single-source dosimetry preceding clinical use. The International Organization for Standardization (ISO) Guide to the Expression of Uncertainty in Measurement (GUM) and the National Institute of Standards and Technology (NIST) Technical Note 1297 are taken as reference standards for uncertainty formalism. Uncertainties in using det...

PURPOSE In this study, we attempted to obtain full dosimetric data for a new (90)Y brachytherapy source developed by the College of Chemistry (Sichuan University) for use in high-dose-rate after-loading systems. MATERIAL AND METHODS The dosimetric data for this new source were used as required by the dose calculation formalisms proposed by the AAPM Task Group 60 and Task Group 149. The active...

The unwanted radiation transmission through the multileaf collimators could be reduced by the jaw tracking technique which is commercially available on Varian TrueBeam accelerators. On the basis of identical plans, this study aims to investigate the dosimetric impact of jaw tracking on the volumetric-modulated arc therapy (VMAT) plans. Using Eclipse treatment planning system (TPS), 40 jaw-track...