Ingestion of amniotic fluid and placenta by rats has been shown to enhance opioid-mediated analgesia. The present studies were designed to examine the effect of several doses and volumes of placenta and amniotic fluid on tail-flick latency in rats treated with 3 mg/kg morphine. The optimal dose of amniotic fluid was found to be 0.25 ml, although 0.50 and 1.0 ml also produced significant enhance...

-Cis-dichlorobis(cyclopentylamine)platinum II (DBCP) belongs to the group of platinum complexes which have recently been reported to have anti-tumour activity. Its cytotoxic activity in CHO cells is not cell-age-dependent, but enhancement of the effect of ionizing radiation is both dose-and cell cycle phase-dependent. In asynchronous cell populations DBCP acts as a dose-modifying factor for ion...

objective: most   neonates admitted to neonatal wards do not tolerate sufficient milk.  recently the effect of erythromycin on increasing feeding tolerance in neonates has been studied. in this study the effectiveness of oral, high dose erythromycin a prokinetic agent was used to enhance feeding tolerance in these neonates.  methods: this prospective randomized controlled clinical trial was con...

AIM To investigated the dose enhancement due to the incorporation of nanoparticles in skin therapy using the kilovoltage (kV) photon and megavoltage (MV) electron beams. Monte Carlo simulations were used to predict the dose enhancement when different types and concentrations of nanoparticles were added to skin target layers of varying thickness. METHODS Clinical kV photon beams (105 and 220 k...

Background: Proton-impact metallic nanoparticles, inducing low-energy electrons emission and characteristic X-rays termed as Coulomb nanoradiator effect (CNR), are known to produce therapeutic enhancement in proton treatment on experimental tumors. The purpose of this pilot study was to investigate the effect of CNR-based dose enhancement on tumor growth inhibition in an iron-oxide nanoparticle...

radiation degradation of chitosan is one of the most important methods to prepare antibacterial oligochitosans. in this study, the effect of solvent on the reduction of degradation dose and enhancement of the antibacterialactivity of chitosan against pectobacterium carotovorum (pc) has been considered.gamma radiation degradation was applied to chitosan as solid and aqueous solution at dose rang...