Mice lacking the hypoxia-inducible transcription factor EPAS1 die at mid-gestation. Despite normal morphological development of the circulatory system, EPAS1-deficient mice display pronounced bradycardia. In addition to the vascular endothelium, EPAS1 is expressed intensively in the organ of Zuckerkandl (OZ), the principle source of catecholamine production in mammalian embryos. EPAS1-deficient...

Se indagan los comportamientos territoriales de las Denominaciones Origen Protegidas del cerdo ibérico. La fuente básica son Pliegos Condiciones, analizados comparativamente desde lógicas sistemas agroalimentarios localizados y sus atributos proximidad en la cadena alimentaria arraigo agroecológico. Ciclos productivos ganaderos agroindustriales se correlacionan con circunscripciones normativas ...

Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor. Classified by the World Health Organization (WHO) as grade IV astrocytoma, GBMs are extremely aggressive, almost always recur, and despite our best efforts, remain incurable. This review describes the traditional treatment approaches that led to moderate successes in GBM patients, discusses standard imaging modaliti...

We present novel algorithms for efficient hierarchical collision detection and propose a hardware architecture for a single-chip accelerator. We use a hierarchy of bounding volumes defined by k-DOPs for maximum performance. A new hierarchy traversal algorithm and an optimized triangle-triangle intersection test reduce bandwidth and computation costs. The resulting hardware architecture can proc...

We present a novel hardware architecture for a single-chip collision detection accelerator and algorithms for efficient hierarchical collision. We use a hierarchy of k-DOPs for maximum performance. A new hierarchy traversal algorithm and an optimized triangle-triangle intersection test reduce bandwidth and computational costs. The resulting hardware architecture can process two object hierarchi...