Galway, Ireland Importance of Cell Interactions in Tissue Engineering of Full-thickness Oral Mucosa Beste Kinikoglu, Céline Auxenfans, Pascal Pierrillas, Pierre Breton, Carole Burillon, Vasif Hasirci, Odile Damour, Corresponding Author: [email protected] Banque de Tissus et Cellules, Hospices Civils de Lyon, Lyon, France METU, BIOMAT, Departments of Biotechnology and Biological Sciences,...

Pyogenic granuloma is a relatively common benign lesion of the skin and/or mucosal surfaces, accounting for 0.5% of all skin nodules in children in the United States alone (Lin et al, 2004). The aetiology is still poorly understood but trauma, hormonal influence, viral oncogenes, microscopic arteriovenous malformations and growth factors (e.g. tumour angiogenesis factor – Patrice et al, 1991) h...

tuberculosis (tb) is an important health problem in developing countries, with varying clinical presentations depending on the organs/systems involved. to study the spectrum of clinical and paraclinical aspects of extra pulmonary tb in children suffering from pulmonary tb. this study has been carried out on 65 children with tuberculosis, admitted in tb wards of national research institute of tu...

Rosacea fulminans (RF), previously known as pyoderma faciale, is a rare presentation of rosacea mostly seen in young women. RF is seen very rarely in men. We present below a case of a fifty-year-old male who presented with RF and was successfully treated with a combination of corticosteroids and isotretinoin.

Les granulomes ou processus centro-faciaux sont caractérisés par une double définition : Clinique par la présence de lésions ulcéronécrotiques extensives siégeant au niveau des voies aériennes supérieures évoluant vers la destruction de la région médio-faciale; et histologiquement par la présence d'un granulome épithéliogiganto cellulaire. Les étiologies sont multiples: infectieuses, inflammato...

some lesions in the oral cavity and mostly on gingiva have predominant predilection towards females, and mostly occur in the first four decades of life when changes in sex hormone levels in blood are obvious. the present study aimed to investigate the presence and distribution of estrogen and progesterone receptors in peripheral giant cell granuloma (pgcg), pyogenic granuloma (pg) and periphera...

Disseminated tuberculosis can present in various ways including prolonged fever / pyrexia of unknown origin, hepatosplenomegaly, lymphadenopathy, meningitis and rarely extreme forms of hematological abnormalities such as pancytopenia and leukemoid reaction. We hereby report a case who presented with short history of fever, associated with vomiting and altered sensorium. He also had evidence of ...

Treatment with interleukin-12 (IL-12) induces leishmanicidal activity in experimental Leishmania donovani infection; therefore, BALB/c mice were injected with anti-IL-12 antibody to define the role of endogenous IL-12 in acquired resistance in this disseminated intracellular infection. Anti-IL-12 administration started 1 day after infection and given for 4 weeks abolished control of visceral pa...

Treatment of tuberculosis, a complex granulomatous disease, requires long-term multidrug therapy to overcome tolerance, an epigenetic drug resistance that is widely attributed to nonreplicating bacterial subpopulations. Here, we deploy Mycobacterium marinum-infected zebrafish larvae for in vivo characterization of antitubercular drug activity and tolerance. We describe the existence of multidru...

Schistosomiasis mansoni is a chronic helminthic disease that affects about 100 million people in the tropics. The worms have a life span of 5 to 10 years, and they live in the mesenteric veins of the host. Lightly infected individuals are asymptomatic or manifest mild intestinal symptoms. Heavily infected individuals often develop severe morbidity with hepatosplenomegaly, sometimes with a fatal...