Background & objective: Globally, breast cancer is the most common malignancy among females. Prohibition (PHB)-I, a homologous protein, was initially introduced as a suppressor gene for amplification process. Further, the protein has a key role in the cell cycle and is capable of inhibiting DNA transcription in many cell types. Therefore, its possible role in different...

Backgrounds: Chemotherapy for treatment of breast cancer uses some drugs to target and destroy the cancer cells. However, most of antineoplastic treatments are non-specific and the innate cells will be damaged. In this study, the effect of Adriamycin/Cytoxan (AC) chemotherapy on status of antioxidant enzymes and Se levels in breast cancer patients was evaluated. Methods: A prospective study, i...

Introduction: There is a lack of information on the extent of dependency between chronic diseases and the survival rate of breast cancer. Until date, none of the models proposed has determined the impact of chronic diseases on breast cancer survival. This study, therefore, aimed to investigate the impacts of chronic diseases such as diabetes, blood pressure, and endocrine di...

Introduction: There is a lack of information on the extent of dependency between chronic diseases and the survival rate of breast cancer. Until date, none of the models proposed has determined the impact of chronic diseases on breast cancer survival. This study, therefore, aimed to investigate the impacts of chronic diseases such as diabetes, blood pressure, and endocrine di...

Background: Breast cancer is an important cause of cancer death among women all over the world. Even in places with low incidence there are reports of an increase in the number of breast cancer patients. The aim of the present study was to report the demographic aspects of breast cancer among patients referred by surgeons for adjuvant therapy in a private cancer clinic during the past five year...

background: embarrassment and shame of visiting a doctor for a breast disease are among psychosocial factors that potentially contribute to delay in seeking medical advice. the purpose of this study is to review the published literature to determine if embarrassment regarding breast examination, diagnosis and treatment is associated with patient delay. methods: we searched pubmed with the follo...

primary sarcoma of the breast is very rare and constitutes less than 1% of all breast cancers. herein, we report a case of pleomorphic rhabdomyosarcoma (prms) of the right breast in a 49-year-old female patient presented with a mass (7 cm × 6.5 cm). mammography and ultrasonography suspected a malignant lesion and a diagnosis of poorly differentiated carcinoma was made on fine needle aspiration ...

background: as the third most frequent cause of cancer death, breast cancer is a common disease worldwide. most of the patients are being diagnosed in the stage that conventional treatments are not effective, and invasion and metastases lead to death. therefore, identification of novel molecular markers to improve early diagnosis, prognosis and treatment of the breast cancer is a necessity. zin...

background & aim: family caregivers of cancer patients are at a high risk of physical, psychological and emotional problems, which could adversely affect their quality of life. this study aimed to evaluate the quality of life of the female caregivers of breast cancer patients in sabzevar, iran. methods: this cross-sectional study was conducted on 105 participants in sabzevar, iran in 2013. subj...