This paper proposed a method for assembly sequence planning for modular product. Community structure were used in assembly sequence. Firstly, GN Algorithm was employed to detecting the module of product, Secondly candidate sets of disassembly sequence can be generated according to the module partition evolution process and priority rules, Lastly, the optimization of disassembly sequence could b...

The N-methyl-D-aspartate (NMDA) receptor is crucial for development and neuroplasticity as well as excitotoxicity. The biochemical basis of the disassembly and reassembly of NMDA receptor has never been reported. Using coimmunoprecipitation, Western blotting, and mass spectrometry, we show that inhibition of tyrosine phosphatases triggers disassembly of NR1, NR2A, and NR2B in cortical NMDA rece...

Modern production conditions demand the application of the concept of distributed production. Today companies are specialized for partial technology processes. Hundreds, sometimes even thousands, of collaborative processes depend on workers’ interaction and communication in product assembly and disassembly phases. RFID technologies can be really helpful in identifying objects in terms of sustai...

In this paper, algorithms are presented in order to determine the best disassembly sequence for a sub-assembly and a system life-cycle model for disassembly-assembly line design. The main contribution consists in the determination of a sequence which has the minimal number of components to disassemble, taken into account several criteria: stability, the geometrical form, operations done in para...

Catecholamine secretion and actin filament disassembly are closely coupled in chromaffin cells. Opioid suppression of catecholamine secretion is fast and transient, both characteristics of actin filament involvement. The aim of the present work was to test the hypothesis that opioids suppress catecholamine secretion via an inhibitory effect on actin filament disassembly. For this purpose we use...

Nuclear pore complexes (NPCs) are large macromolecular structures embedded in the nuclear envelope (NE), where they facilitate exchange of molecules between the cytoplasm and the nucleoplasm. In most cell types, NPCs are evenly distributed around the NE. However, the mechanisms dictating NPC distribution are largely unknown. Here, we used the model organism Caenorhabditis elegans to identify ge...

Software deobfuscation is a crucial activity in security analysis and especially, in malware analysis. While standard static and dynamic approaches suffer from well-known shortcomings, Dynamic Symbolic Execution (DSE) has recently been proposed has an interesting alternative, more robust than static analysis and more complete than dynamic analysis. Yet, DSE addresses certain kinds of questions ...

BACKGROUND In motile cells, protrusion of the lamellipodium (a type of cell margin) requires assembly of actin monomers into actin filaments at the tip of the lamellipodium. The importance of actin-filament disassembly in this process is less well understood, and is assessed here using the actin drug jasplakinolide, which has two known activities - inhibition of filament disassembly and inducti...

Thrombospondin (TSP) signals focal adhesion disassembly (the intermediate adhesive state) through interactions with cell surface calreticulin (CRT). TSP or a peptide (hep I) of the active site induces focal adhesion disassembly through binding to CRT, which activates phosphoinositide 3-kinase (PI3K) and extracellular signal-related kinase (ERK) through Galphai2 proteins. Because CRT is not a tr...

The dynamic structure of individual nucleosomes was examined by stretching nucleosomal arrays with a feedback-enhanced optical trap. Forced disassembly of each nucleosome occurred in three stages. Analysis of the data using a simple worm-like chain model yields 76 bp of DNA released from the histone core at low stretching force. Subsequently, 80 bp are released at higher forces in two stages: f...