In this paper we demonstrate that 3D printing with a digital light processor stereolithographic (DLP-SLA) 3D printer can be used to create high density microfluidic devices with active components such as valves and pumps. Leveraging our previous work on optical formulation of inexpensive resins (RSC Adv., 2015, 5, 106621), we demonstrate valves with only 10% of the volume of our original 3D pri...

To address the problem of low integration and efficiency reverse osmosis desalination system, an energy-recovery type incurve multiple acting pump is developed with integrated functions a high-pressure pump, energy recovery device booster pump. In order to determine its flow range suppress cavitation generation, mathematical model port plate established, combining realizable k-ɛ turbulence Schn...

Collecting lymphatic vessels share functional and biochemical characteristics with cardiac muscle; thus, we hypothesized that the lymphatic vessel pump would exhibit behavior analogous to homeometric regulation of the cardiac pump in its adaptation to elevated afterload, i.e., an increase in contractility. Single lymphangions containing two valves were isolated from the rat mesenteric microcirc...

Postexcitatory depression (PED) and adaptation were examined in slowly adapting aortic baroreceptors of normotensive rats (NTR) and spontaneously hypertensive rats (SHR); an aortic arch-aortic nerve preparation in vitro was used. PED was elicited either mechanically by employing single or double pressure steps, or electrically by antidromic stimulation of the aortic nerve. During PED the axon o...

Blaustein, Mordecai P., Jin Zhang, Ling Chen, and Bruce P. Hamilton. How does salt retention raise blood pressure? Am J Physiol Regul Integr Comp Physiol 290: R514–R523, 2006; doi:10.1152/ajpregu.00819.2005.—A critical question in hypertension research is: How is long-term blood pressure controlled? Excessive NaCl ingestion or NaCl retention by the kidneys and the consequent tendency toward pla...

OBJECTIVES Real-time monitoring of the aortic valve function and the loading state of the left ventricle (LV) during mechanical circulatory support is essential. Therefore, we developed a system that determines accurately the aortic valve closing moment based on integrals derived from the pump inlet pressure and the pump power [pressure-power area (PPA)]. METHODS A Deltastream diagonal pump w...

Pump-probe-based Photoacoustic imaging is an innovative technique for high-specificity molecular in deep tissues. In comparison to conventional photoacoustic imaging, this method effectively eliminates the interference from blood and other background signals, enabling detection of subtle target molecules. Additionally, by manipulating time delay between pump probe lasers, it facilitates non-inv...

Introduction In order to cancel Gedeon streaming in traveling wave thermoacoustic devices, a jet pump can be used [2, 3]. Due to its asymmetric shape an asymmetry in the minor losses during each acoustic cycle occurs that yields a time-averaged pressure drop across the jet pump. By balancing the time-averaged pressure drop across the jet pump with that which exists across the regenerator of a t...

Reports from several laboratories suggest the presence of an ouabainlike compound in plasma and various animal tissues, particularly during acute volume expansion and in low-renin hypertension. It has been hypothesized that this compound, through inhibition of the Na(+)-K+ pump, can constrict blood vessels, enhance vasoconstriction in response to agonists, increase cardiac contractility, raise ...

Fifty-nine patients with severe chronic heart failure were given pirbuterol, a beta agonist with vasodilator and positive inotropic properties. The acute haemodynamic responses to both single (20 patients) and incremental doses (39 patients) were measured. Pirbuterol increased cardiac index and reduced left ventricular filling pressure and systemic vascular resistance with only small changes in...