The levels of milk-specific mRNAs (a-casein, whey acidic protein) and proteins (casein, a-lactalbumin) were examined in the DIM series of mammary preneoplastic outgrowth lines and tumors. The constitutive production of casein protein was variable among the preneoplastic DIM outgrowth lines maintained in virgin mice. Outgrowth line DIM-2 con sistently expressed a very low level of casein mRNA an...

Two-dimensional angular correlation of annihilation radiation (2D-ACAR) and Compton scattering are both powerful techniques to investigate the bulk electronic structure crystalline solids through momentum density electrons. Here we apply methods a single crystal Pd study electron occupancy in first Brillouin zone, point out complementary nature two techniques. To retrieve 2D spectra from 1D pro...

We prove the following three closely related results: (1) Every finite simple group G has a profinite presentation with 2 generators and at most 18 relations. (2) If G is a finite simple group, F a field and M is an FG-module, then dim H.G;M/ .17:5/ dim M . (3) If G is a finite group, F a field and M is an irreducible faithful FG-module, then dim H.G;M/ .18:5/ dim M . Mathematics Subject Classi...

This paper investigates the behavior of the Hausdorr dimensions of the limit sets n and of a sequence of Kleinian groups ? n ! ?, where M = H 3 =? is geometrically nite. We show if ? n ! ? strongly, then: (a) M n = H 3 =? n is geometrically nite for all n 0, (b) n ! in the Hausdorr topology, and (c) H: dim((n) ! H: dim((), if H: dim(() 1. On the other hand, we give examples showing the dimensio...

Abstract Let $F$ be a Bedford–McMullen carpet defined by independent integer exponents. We prove that for every line $\ell \subseteq \mathbb{R}^2$ not parallel to the major axes, $$\begin{align*} & \dim_H (\ell \cap F) \leq \max \left\lbrace 0,\, \frac{\dim_H F}{\dim^* F} \cdot (\dim^* F-1) \right\rbrace\end{align*}$$and \dim_P \frac{\dim_P \right\rbrace,\end{align*}$$where $\dim ^*$ is Fur...

(c) Columns of A are independent. (d) A is tall (i.e., n ≤ m) and full-rank (i.e., rank(A) = min(m,n) = n). Solution: We will show the chain of equivalences (a) =⇒ (b) =⇒ (c) =⇒ (d) =⇒ (a). (a) =⇒ (b): By the rank–nullity theorem, we have dim(N (A)) + rank(A) = n, which implies rank(A) = n (since dim(N (A)) = 0). Since rank(A) = rank(A ), we then have rank(A ) = n. Since rank is equivalent to t...

Modulation of the immune system by cancer protective food bioactives has preventive and therapeutic importance in prostate cancer, but the mechanisms remain largely unclear. The current study tests the hypothesis that the diet-derived cancer protective compounds, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), affect the tumor microenvironment by regulation of inflammatory responses in...

1,1-Bis(3'-indolyl)-1-(p-t-butylphenyl)methane (DIM-C-pPhtBu) is a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, and treatment of SKOV3 ovarian cancer cells with this compound (5 micromol/L) inhibits cell proliferation, whereas up to 15 micromol/L rosiglitazone had no effect on cell growth. DIM-C-pPhtBu also inhibits G0-G1 to S phase cell cycle progression and this is li...

BACKGROUND The development of 3, 3'-diindolyl methane (DIM) resistant parasite Leishmania donovani (LdDR50) by adaptation with increasing concentrations of the drug generates random mutations in the large and small subunits of heterodimeric DNA topoisomerase I of Leishmania (LdTOP1LS). Mutation of large subunit of LdTOP1LS at F270L is responsible for resistance to DIM up to 50 µM concentration....