Declaration of interest None. Trends in disease incidence are important for conceptualising disease aetiology and planning health services. Several studies have used meta-analysis to determine whether eating disorder incidence has changed over time, although these have largely focused on anorexia nervosa. Prior results indicate a small global increase in the incidence of anorexia nervosa throug...

BACKGROUND Gastrointestinal cancers are characterized by a male predominance, suggesting a role of sex hormones. We hypothesized that digitalis medication, due to its estrogenic properties, decreases the risk of male-predominated gastrointestinal cancers. RESULTS Long -term digitalis use (≥2 years) was followed by decreased risk for several gastrointestinal cancers, but associations were stat...

OBJECTIVE To compare flow-mediated vasodilatation in patients with anorexia nervosa and healthy subjects. BACKGROUND Endothelial dysfunction is present in the patients with anorexia nervosa. However, flow-mediated vasodilatation in the patients with anorexia nervosa in comparison with control subjects has not been yet evaluated. METHODS Flow-mediated vasodilatation in the brachial artery wa...

BACKGROUND Although there is much literature on adolescent suicide, combined effects of depression and anorexia nervosa on suicide were rarely investigated. The aims of this study are to examine the association between anorexia nervosa and suicidal thoughts and explore the interaction between anorexia nervosa and depression. METHODS This is a cross-sectional study, in the study, a sample of 8...

mai and he also pointed out that heparinised animals were more resistant to digitalis poisoning than control ones. On a small but well controlled series of rabbits Werch (1943) found that when digifolin was given I/V to the rabbits in comparatively large amount, it caused a significant decrease in the coagulation time of blood. In addition there are many other reports which favour the above hyp...

BACKGROUND Clinical and population-based studies report increased prevalence of autism spectrum disorders (ASD) in individuals with anorexia nervosa and in their relatives. No nationwide study has yet been published on co-occurrence of these disorders. AIMS To investigate comorbidity of ASD in individuals with anorexia nervosa, and aggregation of ASD and anorexia nervosa in their relatives. ...

AS I feci myfelf much interefted for the fate of the Digitalis purpurea, of which fome notice has been lately taken in the London Medical Journal *, and fear, from the reprefentation there made, that the fame deftiny may await it, which the Peruvian bark formerly met with, I am defirous of communicating to you fome general account of the effe&s which I have experienced from its adminiftration ;...