نتایج جستجو برای: diffuse large b cell lymphoma

تعداد نتایج: 3216825  

2017
Martine van Keimpema Leonie J. Grüneberg Esther J.M. Schilder-Tol Monique E.C.M. Oud Esther A. Beuling Paul J. Hensbergen Johann de Jong Steven T. Pals Marcel Spaargaren

The forkhead transcription factor FOXP1 is generally regarded as an oncogene in activated B cell-like diffuse large B-cell lymphoma. Previous studies have suggested that a small isoform of FOXP1 rather than full-length FOXP1, may possess this oncogenic activity. Corroborating those studies, we herein show that activated B cell-like diffuse large B-cell lymphoma cell lines and primary activated ...

2015
Pooja Advani Jason Starr Abhisek Swaika Liuyan Jiang Yushi Qiu Zhimin Li Han W. Tun

Primary central nervous system (PCNSL) lymphoma is an aggressive extranodal non-Hodgkin lymphoma, and most cases are classified as diffuse large B-cell lymphoma (DLBCL) by histology. T-cell/histiocyte-rich large B-cell lymphoma (TCRLBCL) represents a distinct subtype of diffuse large B-cell lymphoma and is characterized by the presence of scattered large neoplastic B-cells in a background of ab...

2014
Violetta V. Leshchenko Pei-Yu Kuo Zewei Jiang Venu K. Thirukonda Samir Parekh

Purpose: Despite advances, there is an urgent need for effective therapeutics for relapsed diffuse large B-cell lymphoma, particularly in elderly patients and primary central nervous system (CNS) lymphoma. Temozolomide (TMZ), an oral DNA-alkylating agent routinely used in the therapy of glioblastoma multiforme, is active in patients with primary CNS lymphoma but the response rates are low. The ...

Journal: :Anticancer research 2014
Vincenzo Dario Mandato Rosalba Palermo Angela Falbo Isabella Capodanno Francesco Capodanno Maria Carolina Gelli Lorenzo Aguzzoli Martino Abrate Giovanni Battista La Sala

BACKGROUND Primary diffuse large B-cell lymphoma of the cervix is a very rare disease, with non-specific clinical presentation. Its prognosis depends on accurate and timely diagnosis and therapy. Moreover, the management of this tumour has never been standardized. CASE REPORT Herein we present a rare case of primary diffuse large B-cell lymphoma of the cervix misdiagnosed as cervical myoma. O...

Journal: :Hematology/Oncology and Stem Cell Therapy 2015

Journal: :Human pathology 2010
Robert F Luo Shuchun Zhao Robert Tibshirani June H Myklebust Mrinmoy Sanyal Rosemary Fernandez Dita Gratzinger Robert J Marinelli Zhi Shun Lu Anna Wong Ronald Levy Shoshana Levy Yasodha Natkunam

CD81 is a tetraspanin cell surface protein that regulates CD19 expression in B lymphocytes and enables hepatitis C virus infection of human cells. Immunohistologic analysis in normal hematopoietic tissue showed strong staining for CD81 in normal germinal center B cells, a cell type in which its increased expression has not been previously recognized. High-dimensional flow cytometry analysis of ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Violetta V Leshchenko Pei-Yu Kuo Zewei Jiang Venu K Thirukonda Samir Parekh

PURPOSE Despite advances, there is an urgent need for effective therapeutics for relapsed diffuse large B-cell lymphoma, particularly in elderly patients and primary central nervous system (CNS) lymphoma. Temozolomide (TMZ), an oral DNA-alkylating agent routinely used in the therapy of glioblastoma multiforme, is active in patients with primary CNS lymphoma but the response rates are low. The m...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Michael E Peskin

I review the status of the model of dark matter as the neutralino of supersymmetry in the light of constraints on supersymmetry given by the 7- to 8-TeV data from the Large Hadron Collider (LHC).

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