PURPOSE Our aim was to compare perfusion magnetic resonance imaging (MRI) and positron emission tomography (PET) using carbon-11 labelled methionine (MET) in gliomas and their value in differentiating tumour recurrence from necrosis. MATERIALS AND METHODS We retrospectively reviewed 28 patients with a high-grade glioma. A total of 33MR perfusions and MET-PET were ultimately analysable for com...

neuromyelitis optica is an inflammatory demyelinating disease (idd) of the cns, which mainly affects optic nerve and spinal cord. autoantibodies against aquaporin-4 also known as nmo-igg have been implicated in the pathogenesis of nmo. we evaluated the sensitivity and specificity of nmo-igg assay for diagnosing nmo patients and differentiating them from ms patients and those with undifferentiat...

We compared 76 99mTc-DISIDA hepatobiliary studies with corresponding liver biopsies in 36 liver transplant patients to determine the histopathologic abnormalities that corresponded to scintigraphic abnormalities in uptake and excretion. Uptake was judged normal if the cardiac blood pool was barely visible or invisible on the ten minute image. Excretion was judged normal if images subsequent to ...

Growth factor-independent clones of myeloid leukemic cells can regain a growth factor-dependent state during differentiation. Loss of viability in these differentiating leukemic cells in the absence of growth factor was associated with DNA fragmentation and morphologic changes typical of programmed cell death (apoptosis). The differentiating leukemic cells could be rescued from apoptosis by a h...

Johan L. bloem. [email protected] Key points -Radiographs supported by epidemiologic data remain the mainstay in differentiating benign from malignant osseous lesions. -MR adds to radiographs in differentiating benign from malignant cartilaginous tumors. -On dynamic MR enhancement of parts of a cartilaginous tumor within 10 sec. of enhancement of a feeding artery is a sign of chondrosarcoma. -E...

The role of Diffusion Weighted Magnetic Resonance Imaging in the evaluation of various intracranial lesions has been evolving and increasing since its initial introduction as newer uses are being explored constantly. We review the imaging features of 68 cases of intracranial tumors and evaluate the role of diffusion weighted imaging in their diagnosis. Diffusion weighted imaging provides additi...

Identification of differentiating muscle cells generally requires fixation, antibodies directed against muscle specific proteins, and lengthy staining processes or, alternatively, transfection of muscle specific reporter genes driving GFP expression. In this study, we examined the possibility of using the robust mitochondrial network seen in maturing muscle cells as a marker of cellular differe...

The difficulty in identifying, differentiating and expressing emotions is a neuropsychological condition called alexithymia. During the last years it has grown the interest of scientific community for alexithymia, in particular in chronic conditions. Crescent literature data demonstrated that a considerable number of SLE patients present difficulty not only in identifying, differentiating, and ...