OBJECTIVE The purpose of this study was to determine whether dietary fat intake above current Acceptable Macronutrient Distribution Range (AMDR) guidelines was associated with greater insulin resistance in black and white children. RESEARCH METHODS AND PROCEDURES We studied 142 healthy children (n = 81 whites, n = 61 blacks), 6.5 to 14 years old. Dietary composition was determined by repeated...

background: studies have shown that zinc and selenium deficiency is common in nonalcoholic fatty liver disease (nafld). however, the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld are not clear enough. the aim of this study was to compare the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld prognos...

The hepatic lipase (LIPC) locus is a well-established determinant of high-density lipoprotein cholesterol (HDL-C) concentrations, an association that is modified by dietary fat in observational studies. Dietary interventions are lacking. We investigated dietary modulation of LIPC rs1800588 (-514 C/T) for lipids and glucose using a randomized crossover design comparing a high-fat Western diet an...

Abstract It has been observed that a constriction of the gut microbiome occurs with high fat diet, and likewise decreased diversity is directly correlated more severe graft-versus-host disease (GvHD) following allogeneic hematopoietic stem cell transplantation. Taken together it plausible not only content, but source dietary could influence microbiota GvHD outcome. We sought to address this que...

Excessive intake of dietary fat is known to be a contributing factor in the development of obesity. In this study, we determined the dose-dependent effects of dietary fat on the development of this metabolic condition with a focus on changes in gene expression in the small intestine. C57BL/6J mice were fed diets with either 10, 20, 30 or 45 energy% (E%) derived from fat for four weeks (n = 10 m...

There are no definitive explanations as to why individuals with hypercholesterolemia, a major cardiovascular risk factor, respond differently to dietary change. Fifty five free-living individuals completed a double crossover trial with two dietary regimens, a high saturated fat diet (providing 21% energy from saturated fat and 3% energy from polyunsaturated fat) and a high polyunsaturated fat d...

Linseed is an important oil crop cultivated worldwide for oil and fiber. Linseed oil has health benefits and disease preventive properties on coronary heart disease, some kinds of cancer, neurological and hormonal disorders. Linseed Linum usitattissimum family Linaceae) has been traditionally used as functional food. Linseed oil is the richest source of ALA, which makes about 55–60% of total fa...

Dietary coconut oil (CO), a source of saturated, predominantly mediumchain fatty acids (FA), reduced enteric methane emission, but also reduced DMI and milk yield in our earlier studies. Here, we examined lactational performance of early lactation cows fed 2 sources of saturated FA, differing in predominant chain lengths. Dietary treatments were: no added fat (CTRL); 2.7% of DM as saturated lon...

background: fat-rich diet may alter oocyte development and maturation and embryonic development by inducing oxidative stress (os) in follicular environment. objective: to investigate the relationship between fat intake and oxidative stress with oocyte competence and embryo quality. materials and methods: in observational study follicular fluid was collected from 236 women undergoing assisted re...