JALYN® (DUTASTERIDE/TAMSULOSIN): A NEW OPTION IN BPH n the U.S., the leading method of contraception is the combination oral contraceptive pill. More than 10 million women aged 15-44 years use the birth control pill as their primary method of contraception.1 Since the first BCP approval in 1960, the FDA has approved many oral contraceptive products. Most of these products use ethinyl estradiol ...

Endometriosis is characterised by the benign growth of endometrial glands and stroma on the surface of peritoneal tissues and other organs. It is generally regarded as an aberrant estrogen-dependent growth condition, which presents with symptoms of chronic pelvic pain, bleeding and infertility. Steroidal progestogens are already widely used in the treatment of the condition, dienogest (Visanne)...

It was the aim of this study to investigate whether assessment of the metabolic stability of selected progestins of the 19-nortestosterone type in human microsomal liver preparations was a suitable approach to predict the oral bioavailability of these drugs in humans. The Michaelis-Menten parameters Vmax and KM,app for norethisterone, levonorgestrel, gestodene, desogestrel, 3-keto-desogestrel, ...

Introduction . Endometriosis is characterised by a chronic course and significantly affects the quality of life young patients. Aim. To study features clinical picture pain syndrome in adolescent girls with genital endometriosis against background 1 year therapy. Materials methods A prospective longitudinal included 32 (14–17 years old) confirmed diagnosis endometriosis. The severity were asses...