Turmeric, the dried yellow rhizome of Curcuma longa, is a common oriental spice that gives curry dishes their characteristic yellowish color and is used in Indian cooking. The active ingredient in turmeric is curcumin, which is approximately 0.5-6.0 % by weight of the root of turmeric. Since 1970, when curcumin first attracted the interest of scientific medical researchers, studies of curcumin ...

BACKGROUND Focal and generalized neuropathies, such as carpal tunnel syndrome and diabetic peripheral neuropathy, have high prevalence among the US population. Primary care physicians are increasingly using computerized electrodiagnostic (EDX) testing to evaluate these patients. The impact of this diagnostic modality on physician diagnostic reasoning and patient management has not been directly...

Among neurological findings in diabetics, increased vibratory perception threshold (VTP) and abnormal ankle jerks are thought to be two of the most common. This study aims to determine the diagnostic value of VPT by C128-vibrometer. Mean VPT in a reference group composed of 278 non-diabetics showed regression with age, so the normal range was determined as lying below M + 2SD for each 10 year a...

Outcome measures can be classified into measures of impairment, disability, and handicap. To investigate the biological effect of treatment, measures of impairment are appropriate. Studies investigating whether patients benefit from treatment in terms of improvement of functional health, however, require disability or handicap measures. In a review of the medical literature between 1978 and 199...

Objective: Diabetic patients suffer from different types of complications associated with peripheral nerves. A clear manifestation of these complications is found in the mouth where neuropathies commonly occur. The measurement of electrical stimulation threshold of teeth signifies premature involvement of peripheral nerves in the teeth. The aim of present study is to compare pulp tester respons...

Pregnancy is associated with increased risk of development and progression of diabetic retinopathy (DR). Although pregnancy does not have any long term effect on DR, progression of retinopathy changes occur in 50%-70% of cases. The greatest risk of worsening occurs during the second trimester and persists as long as 12 months postpartum. The other factors found to be associated with its progres...

Diabetic neuropathy is common, under or misdiagnosed, and causes substantial morbidity with increased mortality. Defining and developing sensitive diagnostic tests for diabetic neuropathy is not only key to implementing earlier interventions but also to ensure that the most appropriate endpoints are employed in clinical intervention trials. This is critical as many potentially effective therapi...

BACKGROUND Sub-Saharan Africa faces an epidemic of diabetes. Diabetes causes significant morbidity including visual loss from diabetic retinopathy, which is largely preventable. In this resource-poor setting, health systems are poorly organized to deliver chronic care with multiple system involvement. The specific skills and resources needed to manage diabetic retinopathy are scarce. The costs ...