Introduction: Ulcerative keratitis is a common condition in horses due to their large, prominent eyes and can be potentially sight limiting if not diagnosed early and treated properly. Superficial, non-infected ulcers commonly heal rapidly; whereas stromal degradation associated with infected ulcers can rapidly progress to perforation of the cornea. This is characterized by increased proteolyti...

Cutaneous mycoses have been rarely reported in Chelonians. A Testudo hermanni adult male showed a thick erosion of the dorsal neck covered by necrotic material. Trichosporon sp. was cultivated, while arthrospores and hyphae were observed in histological sections. The causative agent was identified as Trichosporon jirovecii by PCR. After a surgical intervention povidone iodine and Iruxol® ointme...

INTRODUCTION Superficial fungal infections affect millions of people throughout the world.1 In Ireland, 10-12% on average, of a general practitioner's (GPs) consultations are skin related.2 Superficial fungal infections characteristically involve the skin or nails with several organisms being responsible. Dermatophyte infections of the feet represent the most common fungal infections in develop...

Dermatophytes, a group of keratinophilic fungi thriving on the keratin substrate are the etiological agents responsible for causing cutaneous infections. Dermatophytosis is currently treated with the commercially available topical and oral antifungal agents in spite of the existing side effects. Treatment of these cutaneous infections with secondary metabolites produced by marine microorganisms...

Fungal Rhinosinusitis (FRS) is a well known entity, but only in more recent times have the types of FRS been more fully defined. In this study, we evaluate the diagnosis of FRS in a single medical center. Cases were divided into 2 main categories, non-invasive and invasive. Non-invasive FRS included fungus ball (FB) and allergic fungal rhinosinusitis (AFRS). Invasive FRS included acute invasive...

Fungal infections of the nose and paranasal sinuses represent a spectrum of diseases ranging from colonization to invasive rhinosinusitis. Clinical manifestations are largely dependent on the immune status of the host, and given the ubiquitous nature of these organisms, exposure is unavoidable. Noninvasive disease includes asymptomatic fungal colonization, fungus balls, and allergic fungal rhin...

OBJECTIVES The purpose of this study was to build and provide a basic database of skin fungal infections for the effective management of skin fungal infections in the future. METHODS We collected health insurance data between the years 2006 and 2010 from the Health Insurance Corporation (Seoul, Korea) and analyzed the data to determine the prevalence and treatment management of skin fungal in...

This study was conducted to evaluate the occurrence of mycoses affecting the feet of soccer players and to compare this results with those in non-athlete individuals of the same age and sex. Initial evaluation consisted of a dermatological examination of the foot in 22 Chinese athletes, 83 Brazilian athletes and 24 Brazilian non-athletes. Scales of plantar skin, interdigital and subungual areas...

Fonsecaea species have been reported as causative agents of chromoblastomycosis, eumycetoma, and fungal pneumonitis. However, Fonsecaea rarely involves the CNS, with few cases of cerebral infection reported in the literature. Fonsecaea monophora may have greater neurotropic potential than other species of this genus. We describe a rare presentation of brain abscess caused by F monophora in an i...

Natural products are often large, synthetically intractable molecules, yet frequently offer surprising inroads into previously unexplored chemical space for enzyme inhibitors. Argifin is a cyclic pentapeptide that was originally isolated as a fungal natural product. It competitively inhibits family 18 chitinases by mimicking the chitooligosaccharide substrate of these enzymes. Interestingly, ar...