Reduction of the original height and width of the alveolar bone of an edentulous site precludes optimal positioning of implant fixtures and may esthetically compromise the prosthesis. Ridge expansion at the time of extraction can prevent the need for ridge reduction and reduces the number of surgical interventions.A patient with a narrow ridge with buccal deformity was treated for the staged pl...

BACKGROUND Bone substation grafts, such as hydroxyapatite (HA) and tricalciumphosphate (TCP), have been extensively used in clinical applications, but evidence suggests that they offer poor osteoinductive properties compared to allografts and autografts. In order to increase bone growth with such grafts, Bone Morphogenetic Protein 2 (BMP-2) was incorporated into a three dimensional reservoir. T...

PURPOSE The aim of this case report is to present the longitudinal results of sinus grafting using a new demineralized bovine bone material (DBBM) in human cases. METHODS A patient with a resorbed maxilla was treated by maxillary sinus grafting using a new deproteinized bovine bone material. After a healing period of 6.5 months, three implants were placed and restored. The patient was periodi...

In this study, succinoglycan was produced from whey and its rheological structural characteristics were elucidated. Eight culture media prepared with different ions for bioconversion of into succinoglycan. The formulation composed deproteinized whey, monobasic potassium phosphate magnesium sulfate allowed the production 13.7 ± 0.43 g/L apparent molar mass estimated to be 9.033 × 105 g/mol polyd...

Traditional pumpkin (Cucurbita moschata) and Japanese (C. maxima) consist of natural polysaccharides. From a scientific basis, polysaccharides could be applied to improve hydration in the cosmetic field. The purified polysaccharide was extracted deproteinized with CaCl2 method. showed higher value physicochemical properties including yield (12.96 ± 0.60%), total content (0.89 0.04 mg/mL), swell...

Autism spectrum disorder is associated with alterations in GABAergic and glutamatergic neurotransmission. Here, we aimed to determine the concentration of GABA, glutamate, glutamine, aspartate, taurine, glycine brain tissue plasma rats prenatally exposed valproic acid (VPA), a well-characterized experimental model autism. Pregnant were injected VPA (600mg/Kg) during twelfth-embryonic-day. Contr...

γ-Aminobutyric acid (GABA) is an inhibitory neurotransmitter having anti-anxiety, stress-reducing and sleep-enhancing effects. The blood GABA concentration has the potential to become a diagnostic index for depression schizophrenia. In this study, we developed method quantification of in human serum by liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS) combine...