OBJECTIVES There are currently no accepted diagnostic criteria for bipolar depression for either research or clinical purposes. This paper aimed to develop recommendations for diagnostic criteria for bipolar I depression. METHODS Studies on the clinical characteristics of bipolar and unipolar depression were reviewed. To identify relevant papers, literature searches using PubMed and Medline w...

The aim of this study was to validate the Dutch version of the Kessler-10 (K10) as well as an extended version (EK10) in screening for depressive and anxiety disorders in primary care. Data are from 1,607 participants (18 through 65 years, 68.8% female) of the Netherlands Study of Depression and Anxiety (NESDA), recruited from 65 general practitioners. Participants completed the K10, extended w...

Ninety two out of one hundred cases of major depressive disorder were followed up for a period of 5 to 10 years after the index diagnosis. 36.6 per cent of the cases, had no recurrence. Out of the 63.4 per cent of the cases who had recurrences, 37.8 per cent cases turned out to be having bipolar affective disorder and remaining 25.6 per cent had major depressive disorder, recurrent type. The ch...

As it occurs for schizophrenia, former subtypes of depressive disorder such as endogenous, reactive, neurotic, retarded, agitated, and anxious types lost their popularities over years. Major depression representing the full picture of depressive disorder and the disthymic disorder as milder and rather chronic types of the latter have been introduced to replace previous ones. However, albeit the...

N Engl J Med 2005;353:1819-34. Copyright © 2005 Massachusetts Medical Society. ecurrent episodes of major depression, which is a common and serious illness, are called major depressive disorder; depressive episodes that occur in conjunction with manic episodes are called bipolar disorder. Major depressive disorder accounts for 4.4 percent of the total overall global disease burden, a contributi...

INTRODUCTION Depression is a well known health problem worldwide. Prevalence of depressive disorders varies in different societies. AIM to determine the prevalence of depressive disorders and some associated factors in Rasht City (Northern part of Iran). MATERIALS AND METHODS 4020 subjects were selected among 394925 residents of Rasht aged between 18-70 during 2003 - 2004. In the first phas...