نتایج جستجو برای: deprenyl
تعداد نتایج: 241 فیلتر نتایج به سال:
The accumulation of β-amyloid in the brain is an early event in Alzheimer's disease. This study presents the first patient with Alzheimer's disease who underwent positron emission tomography imaging with the amyloid tracer, Pittsburgh Compound B to visualize fibrillar β-amyloid in the brain. Here we relate the clinical progression, amyloid and functional brain positron emission tomography imagi...
Background Neuroinflammation, which receives ever increasing interest in neurodegenerative diseases, comprises a heterogeneous cascade of events that are thought to be related the downstream neurodegeneration. The aim this study was evaluate binding 11C-Deuterium-L-Deprenyl PET (DED) as measure reactive astrocytes patients with different dementia disorders, and assess its association other dise...
Monoamine oxidase is an outer mitochondrial membrane protein that catalyzes the deamination of a number of neurotransmitters and dietary amines. To determine the roles of the carboxyl-terminal amino acids on the activity and solubility of human monoamine oxidase (MAO B), 10 sequential mutants were made with stop codons at amino acid positions 511, 504, 498, 492, 486, 481, 476, 467, 417, and 397...
Deprenyl is a selective inhibitor of brain MAO-B in the long-term treatment of Parkinsons's disease.
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