BACKGROUND Major Thalassemia is an autosomal recessive disease with complications, mortality and serious pathology. Today, the life expectancy of patients with major thalassemia has increased along with therapeutic advances. Therefore, they need lifelong care, and caring for them would incur many costs. Being aware of the patients' costs can be effective for controlling and managing the costs a...

background: heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. we studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta thalassemia intermedia, and a control group. methods: eighty asymptomatic patients with thalassemia major and 22 asymptomatic cases with thalas...

During the last two decades conventional therapy has improved the prognosis of thalassemia. However, despite such improvement it still remains a progressive disease with treatment-related complications such as hepatitis, liver fibrosis, and cardiac disease. Bone marrow transplantation (BMT) can prevent or delay progression of the aforementioned complications. The importance of clinical research...

thalassemia major is a genetic blood disorder that is detected by the symptoms of chronic and severe anemia, failure to thrive, an enlarged liver and spleen, bone deformities particularlya deformed face and bulging forehead. due to changes in physical appearance, the disease can influence on other aspects of the patient's life, so the disease could strongly impact on the mental health of t...

background: since the reduction of mental health in patients with thalassemia may affect the quality of life and cause dysfunction in various dimensions, so the assessment of this disorder is necessary to choose the appropriate treatment. therefore, the aim of this study was to investigate the mental health and quality of life in patients with thalassemia major. methods: in this cross-sectional...

background: β-thalassemia is an autosomal hemoglobinopathy with inconsistent universal distribution. among patients with thalassemia diverse non-siderotic complications distinctly influence the attribute of life, including zinc deficiency due to varied etiologies. the objective of the present study was to determine zinc levels in patients with β-thalassemia major and its correlation with matern...

aim: the aim of this study is to assess the growth parameters, vitamin d, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy. patients and methods: in a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group....

Background: Thalassemia is an inherited disease. major patients are transfusion-dependent and very much prone to transfusion-transmitted viral infections. So, this study was conducted determine the prevalence various determinants, contributing in blood transfusion transmitted infection among them. Methodology: A 12-month longitudinal research on thalassemia who met inclusion criteria were regis...

B eta-thalassemias are heterogeneous autosomal recessive hereditary anemias characterized by reduced or absent b globin chain synthesis. The resulting relative excess of unbound a globin chains precipitate in erythroid precursors in the bone marrow, leading to their premature death and, hence, to ineffective erythropoiesis. b-thalassemia phenotypes are variable, ranging from the severe transfus...