A 21 yr old with deep breathing and awake apnoea, who had recurrent hypoxaemia and hypercapnia without sleep apnoea, was presented. Although the organic abnormality responsible for the breathing disturbance was not found, administration of acetazolamide facilitated several breaths between sighs, and the patient's hypoxaemia with hypercapnia improved. Some patients who have abnormalities in the ...

Data-driven computational neural network models have been used to study mechanisms for generating the motor patterns for breathing and breathing related behaviors such as coughing. These models have commonly been evaluated in open loop conditions or with feedback of lung volume simply represented as a filtered version of phrenic motor output. Limitations of these approaches preclude assessment ...

OBJECTIVE To investigate whether the cardiac R-R interval variation (RRIV) is of value in differentiating patients with Parkinson's disease (PD) from multiple system atrophy (MSA). BACKGROUND RRIV assessment is a simple procedure, reflecting mainly vagal efferent activity. Reduced RRIV was reported in MSA. METHODS RRIV at rest and after 120 s of deep breathing was assessed blindly to clinic...

OBJECTIVE To investigate the respiratory and postural adaptations associated with mouth and nasal breathing and to evaluate the associations of such adaptations in mouth breathers' self-perceived quality of life. METHOD Cross-sectional study with mouth breathers (initial n=116 and final n=48) and nasal breathers (initial n=131 and final n=24) from elementary school, aged between 7 and 14 year...

Elevation of the ribs and expansion of the rib cage result from the co-ordinated action of the rib cage muscles. We wished to review the action and interaction of the rib cage muscles during ventilation. The parasternal intercostal muscles appear to play a predominant role during quiet breathing, both in humans and in anaesthetized dogs. In humans, the parasternal intercostals act in concert wi...

The effectiveness of three deep breathing techniques was evaluated in 98 male patients after coronary artery bypass graft surgery in a randomized trial. The techniques examined were deep breathing with a blow bottle-device, an inspiratory resistance-positive expiratory pressure mask (IR-PEP) and performed with no mechanical device. Pulmonary function and roentgenological changes were evaluated....

R-R intervals and R-R interval variation were measured in 2 selected groups of diabetic subjects; 1 group was selected because vagal control of the heart appeared normal, the other group was selected because they lacked vagal control of the heart. The means of the R-R intervals for the 2 groups were not significantly different under various conditions (sleeping, lying, during deep breathing, si...

Heart rate variation in deep breathing, a sensitive non-invasive measure of cardiac parasympathetic activity, was measured in 63 patients with coronary artery disease, in 22 patients with atypical chest pain, and in 20 healthy symptom free volunteers. There was significantly less heart rate variation in deep breathing in the patients with coronary artery disease than in the healthy subjects. Tw...

athlete, the thought of completing strenuous exercise like running 26.1 miles or pitching a baseball game while suffering from asthma is almost un thinkable. Having taken up yoga recently, I am keenly aware of the power and importance of deep breathing in a fitness routine. It almost goes without saying that breathing is fundamental not only to athletes, but to all humans. Conditions that threa...

Sir, we have read the paper by S. Preau et al. “Hemodynamic changes during a deep inspiration maneuver predict fluid responsiveness in spontaneously breathing patients” with great interest. Based on the fundamental ideas of dynamic hemodynamic monitoring, inducing cardiac preload variations and monitoring corresponding pulse pressure variations [1], the paper presents a novel technique of varyi...