Background: Piper guineense (PG) and Sesamum indicum (SI) have been shown to be rich sources of antioxidants and other health benefits; hence, we evaluated the impact of its consumption in hypercholesterolemic model on lipid metabolism. Methods: Forty-eight animals were divided into eight groups of six rats each. Rats were given cholesterol (40 mg/0.3ml), PG and SI extract (100 and 200 mg/kg), ...

Morphine withdrawal usually results in unsuccessful outcomes. Despite partial benefits from alternative substances such as methadone, its use may not lead to the desired result due to the lack of mental tranquility during the withdrawal period. In this study, by means of an animal model, morphine itself was used to manage morphine dependence. Forty mice were divided into 5 groups, in which 4 gr...

background: antibiotic therapies used in treatment of many diseases have adverse effects on fertility. this review analyzes previous comparative studies that surveyed the effects of two common groups of antibiotics on male fertility. objective: to evaluate histo-pathological effects of fluoroquinolones and aminoglycosides on sperm parameters and male reproductive tissue. materials and methods: ...

the aim of this study was to examine the effect of swimming submaximal training and cadmium consumption on cardiac hif1-α and vascular endothelial growth factor (vegf) in pregnant rats. 32 pregnant wistar rats were randomly divided into 4 groups: cadmium, swimming, cadmium+swimming and control. experimental groups performed the swimming protocol for 3 weeks, 5 sessions a week for 60 minutes per...

Phenolic profiles and antioxidant properties of purple wheat varieties were investigated to document the effects of bread-making. Bread crust and crumb along with samples collected after mixing, 30 min fermenting, 65 min fermenting, and baking were examined. Free phenolic content (105.4 to 113.2 mg FAE/100 g) significantly (p < 0.05) increased during mixing, fermenting, and baking (65% to 68%)....

Introduction: Prostate cancer (PrC) is the fifth most common malignancy worldwide and the second most common malignancy in men. Currently, robotic-assisted laparoscopic radical prostatectomy (RARP) has become a popular treatment for localised PrC treatment worldwide. We aimed to assess the learning curve of RARP in our institution. Methods: A total of 391 patients who underwent RARP in our clin...

in this expriment, the effect of different levels of ziziphus zizyphus(zz) (0, 30 or 60 mg) on fermentation parameters, total protozoa population  and three sub family of protozoa  entodiniinae, ophryscolecinae, diplodiniinae and family of isotrichdaeandmethane gas production was assessed using in vitro method and a completely randomized design. the rate of gas production for the insoluble frac...

BACKGROUND Lung cancer is one of the most frequently diagnosed malignancies in the world, thus developing novel anticancer reagents for lung cancer treatment is critical. METHODS We performed cell counting kit-8 and cell colony formation assays to investigate the role of UNBS5162 in the proliferation of A549 cells. Invasion and migration assays were applied to study the inhibitory effect of U...