نتایج جستجو برای: decompensated cryptogenic cirrhosis

تعداد نتایج: 32748  

2017
Jim Young Nina Weis Harald Hofer William Irving Ola Weiland Emiliano Giostra Juan Manuel Pascasio Lluis Castells Martin Prieto Roelien Postema Cinira Lefevre David Evans Heiner C. Bucher Jose Luis Calleja

BACKGROUND There is limited evidence for the effectiveness of daclatasvir in patients whose hepatitis C threatens their life expectancy. The Named Patient Program in Europe included patients with advanced chronic hepatitis C, a life expectancy of less than 12 months and no other treatment options. METHODS A retrospective multi-country cohort of patients with chronic hepatitis C who received d...

2017
Kate Childs Elliot Merritt Aisling Considine Alberto Sanchez-Fueyo Kosh Agarwal Marc Martinez-Llordella Ivana Carey

BACKGROUND Sustained virological response rates (SVRs) to directly acting antiviral (DAA) therapy for hepatitis C virus (HCV) are lower in decompensated cirrhosis. Markers of innate immunity predict nonresponse to interferon-based HCV treatment; however, whether they are associated with the response to DAAs in patients with decompensation is not known. METHODS Information on demographics, adh...

Journal: :Surgery, Gastroenterology and Oncology 2023

Background: One of the most common and dangerous consequences in individuals with decompensated cirrhosis is SBP. Early antibiotic treatment crucial for effective lowering death rate. A modulator immune response infection PGE2. Aim Study: To analyze how Prostaglandin E2 ascites polymorphic nuclear cell count affect cirrhotic diseased individual mortality prognosis.

Journal: :Clinical science and molecular medicine 1977
J Díaz Gil I Rossi P Escartín J M Segovia M Gosálvez

1. Mitochondria and microsomal fractions have been isolated from liver biopsies from patients with alcoholic cirrhosis, cryptogenic cirrhosis or chronic aggressive hepatitis. 2. Cirrhotic livers yieled fewer mitochondria than normal liver. 3. The most significant change was a decrease in mitochondrial respiratory control. Cirrhotic microsomal fractions had a 50% diminution in cytochrome b5 and ...

2012
Agustin Castiella

Hereditary hemochromatosis (HH) is the most frequent genetic disease in populations of European origin. The HH gene was cloned by Feder et al. in 1996, and 2 major mutations were discovered: C282Y and H63D. Geographical differences with mutation frequencies have been published (1, 2) with a decreasing gradient of occurrence in Europe from north to south. HH leads to liver iron overload and rais...

Journal: :hepatitis monthly 0
hossein sendi the liver-biliary-pancreatic center, cannon research center, carolinas medical center, charlotte, nc, usa; department of biology, university of north carolina at charlotte, charlotte, nc, usa; corresponding author at: hossein sendi, liver-biliary-pancreatic center,cannon research center, carolinas medical center, charlotte, nc28203, charlotte, nc, usa. tel.: +1-7047872786, fax: +1-7043551980, e-mail: hossein sendi 1) the liver-biliary-pancreatic center, cannon research center, carolinas medical center, charlotte. 2) department of biology, university of north carolina at charlotte, charlotte, usa +1-7047872786, [email protected]; 1) the liver-biliary-pancreatic center, cannon research center, carolinas medical center, charlotte. 2) department of biology, university of north carolina at charlotte, charlotte, usa +1-7047872786, [email protected] marjan mehrab-mohseni the liver-biliary-pancreatic center, cannon research center, carolinas medical center, charlotte, nc, usa marjan mehrab-mohseni the liver-biliary-pancreatic center, cannon research center, carolinas medical center, charlotte, usa

Journal: :Annals of hepatology 2012
Neeral L Shah Patrick G Northup Stephen H Caldwell

BACKGROUND The relative incidence of bleeding and thrombotic events and the use of blood products in hospitalized cirrhosis patients have not been widely reported. We aimed to estimate the magnitude of bleeding events and venous thrombosis in consecutive hospitalized cirrhotic patients over a finite time period and to examine the amount and indications for blood product use in cirrhosis patient...

2013
Seyed Mohsen Dehghani Mohammad Hadi Imanieh Mahmood Haghighat Abdorrasoul Malekpour Zeinab Falizkar

BACKGROUND Liver cirrhosis is one of the major causes of hospitalization and mortality in children. A wide spectrum of disorders including developmental abnormalities, infections, metabolic and genetic disorders can lead to liver cirrhosis in pediatric patients. Determination of its etiology is important for treatment, prevention of progressive liver damage, family counseling and prioritizing l...

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