Deceased-donor and live-donor kidneys are the two sources for transplantation, and these sources are utilized via two different programs. One of these programs, a paired kidney donation (PKD), involves two donor-patient pairs, for each of whom transplantation from donor to intended recipient is not possible due to medical incompatibilities, but such that the patient in each couple could receive...

BACKGROUND Literature review suggests that adherence to immunosuppressive drugs may be lower in recipients of living than of deceased donor kidney grafts, possibly because of profile differences. OBJECTIVE To compare the level of immunosuppressive adherence levels between patients with deceased and living (-related; -unrelated) donor grafts in Switzerland. METHODS Using data from two simila...

BACKGROUND Although organ donors are rigorously tested, occasionally an unidentified donor disease can be transmitted to the recipient. These conditions include malignancies, infections, and, rarely, congenital diseases. CASE REPORT We report a case of an inadvertent transmission of polycystic kidney disease from a 40-year-old trauma victim to both kidney recipients. There was no family histo...

Organ donation after brain death provides the most important source for deceased organs for transplantation, both because of the number of potential organ donors that it makes available and also because of the unparalleled viability of the organs retrieved. Analysis of worldwide deceased organ donation rates demonstrates that all countries with high deceased organ donation rates (>20 donors per...

INTRODUCTION Existing methods to predict recipient allograft function during deceased-donor kidney procurement are imprecise. Understanding the potential renal reparative role for monocyte chemoattractant protein-1 (MCP-1), a cytokine involved in macrophage recruitment after injury, might help predict allograft outcomes. METHODS We conducted a sub-study of the multicenter prospective Deceased...

Background: Obesity can be a barrier to live donor selection and there are reports of obese live kidney donors (OLKDs) undergoing bariatric surgery prior to donation. While this practice has potential promise, the risks associated with it are unclear. Thus, our aim was to evaluate the advantages and disadvantages of this practice. Design: Risks and benefits were ascertained from the literature....

Kidney transplantation has become the preferred mode of treatment for patient with end stage renal disease (ESRD) after incorporating into clinical practice in the 1960s. With the rising increase in ERSD worldwide and higher life expectancy, the need for kidney transplants is rising and the gap between deceased donors and patients on the waiting list is becoming wider. Living donors are subject...