it is a great pleasure to receive two valuable comments about our article regarding sudden cardiac death (scd) in young athletes from two well known experts working in the field of preparticipation evaluation and prevention of sports injuries. we, as authors, generally agree with both authors' comments. however, some considerations should be re-emphasized here. .....

seizure activity has been proposed to result in the generation of reactive oxygen species (ros), which then contribute to seizure-induced neuronal damage and eventually cell death. although the mechanisms of seizure-induced ros generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. we aim to determine the sources of seizure-induced ros and ...

Introduction: Medical students should be familiar with the endof life ethical issues and its considerations. For teaching end oflife care to medical students, literature is a source of excellentnarratives of patients with experiences of terminally ill conditionin their journey through suffering and one of the most favouritebioethics literature readings has been the death of Ivan Ilych byTolstoy...

programmed cell death-1 (pd-1) and its ligands, pd-l1 and pd-l2, have been regarded as important immune system regulatory molecules. the aberrant expression of the molecules has been related to several autoimmune disorders. this study is aimed to assess the mrna expression level of pd-1, pd-l1, and pd-l2 molecules in the peripheral blood mononuclear mells (pbmcs) from multiple sclerosis (ms) pa...

organ donation is an integral part of the health care system. many patients who have had an accident or have undergone a progressive disease are in need of an organ transplant and if they do not receive the required organ they would die. it is important to know that the most important source of organ donation is the brain death patients. it is highly essential to determine the pivotal factors t...

colloid cysts are mucous-filled masses with an outer fibrous layer. these cysts are rare developmental malformation and not a true neoplasm. they usually found incidentally and are asymptomatic; but in some cases may associate with rapid neurologic deterioration, herniation, and sudden death. recognition of this rare but important diagnosis may result in decreasing mortality. in this report, we...