We study the notions of positive cone, characteristic and C-characteristic in (Krasner) hyperfields. demonstrate how these interact order to produce interesting results theory For instance, we provide a criterion for deciding whether certain hyperfields cannot be obtained via Krasner’s quotient construction. prove that any integer (larger than 1) can realized as some infinite hyperfield an anal...

Nowadays, the significance of keeping equipment function properly each time is obvious. If equipment fails during its use, it may have disastrous consequences. Estimating remaining useful life (RUL) of equipment is a key to prevent such calamities, improve its reliability, provide security and reduce unnecessary maintenance and operational cost. The evolution and tracking of damage is the found...

This disease, which has also been described as cranial arteritis and giant-cell arteritis, was first established as a clinical and pathological entity by Horton and others (1934), though there is evidence that single cases were described before this (Andersen, 1947). Since 1934, over seventy cases have been reported in the literature from U.S.A., Great Britain, France, and Scandinavia. These ha...

The main characteristic of senescence is its stability which relies on the persistence of DNA damage. We show that unlike fibroblasts, senescent epithelial cells do not activate an ATM-or ATR-dependent DNA damage response (DDR), but accumulate oxidative-stress-induced DNA single-strand breaks (SSBs). These breaks remain unrepaired because of a decrease in PARP1 expression and activity. This lea...

We systematically study and compare damage spreading at the sparse percolation (SP) limit for random Boolean and threshold networks with perturbations that are independent of the network size N. This limit is relevant to information and damage propagation in many technological and natural networks. Using finite-size scaling, we identify a new characteristic connectivity Ks, at which the average...

A recurrent connectionist network was trained to output semantic feature vectors when presented with letter strings. When damaged, the network exhibited characteristics that resembled several of the phenomena found in deep dyslexia and semantic-access dyslexia. Damaged networks sometimes settled to the semantic vectors for semantically similar but visually dissimilar words. With severe damage, ...

Actin filaments assemble inside the nucleus in response to multiple cellular perturbations, including heat shock, protein misfolding, integrin engagement, and serum stimulation. We find that DNA damage also generates nuclear actin filaments—detectable by phalloidin and live-cell actin probes—with three characteristic morphologies: (i) long, nucleoplasmic filaments; (ii) short, nucleolus-associa...

Psoriatic arthritis (PsA) has historically been considered a milder rheumatic disease not yielding significant clinical damage. However, recent studies have shown that PsA can be deforming and debilitating and that joint damage can be severe. Traditionally, joint damage has been recorded using plain radiographs. Characteristic radiographic features of PsA include joint erosions, joint space nar...

Acute graft-versus-host disease (GVHD), the major complication of allogeneic bone marrow transplantation (BMT), limits the application of this curative but toxic therapy. Studies of inflammatory pathways involved in GVHD in animals have shown that the gastrointestinal (GI) tract plays a major role in the amplification of systemic disease. Damage to the GI tract increases the translocation of in...