نتایج جستجو برای: daclizumab

تعداد نتایج: 624  

Journal: :The Journal of Experimental Medicine 1990
I Espinoza-Delgado J R Ortaldo R Winkler-Pickett K Sugamura L Varesio D L Longo

We investigated the expression of IL-2R subunits in human monocytes using the TU27 mAb, which recognizes the p75 chain, and anti-Tac mAb, which recognizes the p55 moiety of the IL-2R. We found that p75 but not p55 is constitutively expressed in more than 90% of fresh human monocytes. Antibody to p75, but not to p55, inhibited the activation of monocytes to a cytotoxic stage induced by IL-2 but ...

Journal: :Neurology - Neuroimmunology Neuroinflammation 2019

2012
J. Nicholas B. Morgan-Followell D. Pitt M.K. Racke A. Boster

The therapeutic landscape for multiple sclerosis (MS) is rapidly changing. Currently, there are eight FDA approved disease modifying therapies for MS including: IFN-β-1a (Avonex, Rebif), IFN-β-1b (Betaseron, Extavia), glatiramer acetate (Copaxone), mitoxantrone (Novantrone), natalizumab (Tysabri), and fingolimod (Gilenya). This review will highlight the experience to date and key clinical trial...

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