background: aging contains morphological and functional deterioration in biological systems. d-galactose (d-gal) generates free radicals and accelerates aging. portulaca oleracea (purslane) may have protective effect against oxidative stress. objective: purslane ethanolic extract effects were evaluated on antioxidant indices and sex hormone in d-gal aging female mice. materials and methods: 48 ...

In galactosemia, prevention of mental retardation depends on early recognition of the disorder and institution of dietary restriction of galactose. We describe an automated fluorometric micromethod for galactose in whole blood spotted on filter paper. Galactose is oxidized by galactose oxidase to D-galacto-hexadialdose and H2O2 and measured as the highly fluorescent condensation product of homo...

Background: The ethno-medical significance of Clerodendrum genus raises the interest towards the characterization of its seed lectin by inexpensive and most effective technique.Objective: The focus of this study is the purification, characterization, and evaluation of the antioxidant and antiproliferative potential of a galactose-specific lectin from Cler...

kefiran, extracted from kefir grains, is a water-soluble, glucogalactan containing almost equal amounts of d-glucose and d-galactose residues. throughout this research, kefiran and xanthan were added at concentrations of 3% (w/w flour basis) to two wheat dough samples to investigate the effects on the rheological and physical properties of french bread. physicochemical properties of wheat and i...

1. Certain sugars were transported across the buccal mucosa by a carrier-mediated mechanism. 2. The metabolic loss of sugars from the mouth in a 5 min test period was negligible. 3. The buccal mucosal transport process was stereospecific for D-glucose and L-arabinose. 4. The absorption of D-glucose, galactose and 3-O-methyl-D-glucose was at least partly dependent on the presence of sodium ions ...

The addition of D-glucose, D-galactose, or D-mannose to culture medium increased survival of heated Chinese hamster ovary cells in a concentration- and time-dependent manner. Heat protection by sugars was not immediate but required prior incubation in the sugar medium before hyperthermia. The degree of heat protection conferred by each sugar and its time dependence differed characteristically: ...

Diseases like widespread diabetes or rare galactosemia may lead to high sugar concentrations in the human body, thereby promoting formation of glycoconjugates. Glycation collagen, i.e. glucose bridges, is nonenzymatic and therefore cannot be prevented any other way than keeping level low. It relates secondary diseases, abundantly occurring aging populations diabetics. However, little known abou...

Two major metabolic disorders are associated with galactose metabolism: galactokinase (ATP : D-galactose1-phosphotransferase, EC 2.7.1.6) deficiency and galactosemia (1) secondary to a deficiency in galactose-i-phosphate uridyl transferase (UTP: a-D-galactose-i-phosphate uridyltransferase, EC 2.7.7.10) activity. One case reported in 1972 (2) described a third enzymatic (UDPglucose 4-epimerase, ...

The reactions of the Escherichia coli D-galactosebinding protein with the ligands D-galactose and Dglucose have been examined by stopped flow rapid mixing techniques. The change in tryptophan fluorescence that occurs with galactose binding is described by a rapid, second order process; no additional phases of fluorescence change were observed. The resultant time courses were fitted to a simple ...

Objective(s): Oxidative stress and apoptosis are the major side effects of doxorubicin (DOX) and the advantages accruing fromexercise and some medicinal herbs in mitigation of these toxic side effects is well documented. But so far, the effects of exercise in combination with medicinal nanoparticles on oxidative stress and apoptosis signaling simultaneously, in liver tissue are unknown. Hence, ...