Objective: Our aim was to investigate the immunohistochemical expression of β-catenin and Sox-2 in adenomatous polyps adenocarcinoma colon also evaluate effects these markers adenoma-carcinoma sequence their association with clinicopathological parameters.
 Methods: Fifty-six tubular adenomas low grade dysplasia (TALGD), 53 high (TAHGD), 44 tubulovillous (TVA), 29 villous (VA) 60 adenocarc...