نتایج جستجو برای: cytokine gene polymorphisms
تعداد نتایج: 1244079 فیلتر نتایج به سال:
After infection with Borrelia species, the risk for developing Lyme disease varies significantly between individuals. Recognition of Borrelia by the immune system is mediated by pattern recognition receptors (PRRs), such as TLRs. While TLR2 is the main recognition receptor for Borrelia spp., little is known about the role of TLR1 and TLR6, which both can form functionally active heterodimers wi...
background: il-10 is an anti-inflammatory cytokine which is involved in tumorigenesis. over production of il-10 and elevated number of il-10 generating mononuclear cells in breast tumor tissue has already been shown. objective: to determine the association of il-10 promoter polymorphisms with increased risk of breast cancer and its association with breast cancer prognostic factors. methods: per...
BACKGROUND Cytokines play an important role in chronic heart failure (HF), but little is known about their involvement in acute decompensated heart failure (ADHF). AIM To evaluate the prognostic role of inflammatory cytokines in patients with ADHF. METHODS Levels of interleukin (IL)-6, tumour necrosis factor alpha (TNF-alpha), IL-10 and N-terminal pro-brain natriuretic peptide (NT-proBNP) w...
Certain cytokine gene polymorphisms have been shown to correlate with outcome of human leukocyte antigen (HLA) identical sibling donor stem cell transplantation (SCT), but in unrelated donor SCT such information is scarce. We have studied the association between cytokine gene polymorphism and transplant-related mortality (TRM) in 182 unrelated SCTs performed at a single center. We found associa...
Background and Aim: Cytokines are believed to play an important role in the regulation of cellular immune response in hepatitis B virus infection. Interleukin 10 is a member of cytokine family. The overall expression of these molecules is mainly controlled by single nucleotide polymorphisms at specific sites on the promoter region of the Interleukin 10 gene. The aim of this study was to a...
objective(s):il-12 as an anti-tumor cytokine and il-33 a novel identified cytokine with both pro- or anti-tumor activities, play important roles in response against tumor cells. our aim was to evaluate the il-12 and il-33 levels and single nucleotide polymorphisms (snp) in their genes in patients with breast cancer. materials and methods:blood samples were collected from 100 patients with breas...
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