BACKGROUND Discontinuations and/or interruptions in aspirin therapy for secondary cardioprotection due to upper gastrointestinal (UGI) complications or symptoms have been shown to increase the risk for subsequent cardiovascular events. PA32540 is a coordinated-delivery, combination tablet consisting of enteric-coated aspirin (EC-ASA) 325 mg and immediate-release (IR) omeprazole 40 mg. METHODS...

Barite is an important additive material to increase the weight of excavation mud. It has been used extensively in the excavation mud industry. The barite particle sizes used in excavation mud is very important. There is a direct relationship between the amount on the sift of 200 and 325 mesh. By reducing particle sizes of the 200 and 325 mesh, the specific gravity of the barite power increased...

PURPOSE We describe a technique for functional MR imaging (fMRI) with high spatial and temporal resolution using a long intravascular half-life gadolinium-based contrast agent, MS-325. METHODS All fMRI measurements used a rat model of sensory cortex activation with forepaw electrical stimulation under alpha-chloralose anesthesia. Standard blood oxygen level-dependent (BOLD) fMRI measurement w...

322 Preoperative Cardiopulmonary Exercise Testing (CPET) in Severe Asthma Patients Ekaterini Syrigou, Anastasios Kallianos, Sotirios Tsimpoukis, Nektaria Makrilia, Ioannis Dannos, Fotis Psarros, and Kostas N. Syrigos. Department of Allergy, and; Oncology Unit, 3rd Department of Medicine, Sotiria General Hospital, Athens School of Medicine, Athens, Greece. Background: Lung resection is still the...

BACKGROUND β-blockers prevent cardiac arrhythmias in patients with chronic heart failure and reduced left ventricular ejection fraction, including ventricular tachycardia/ventricular fibrillation (VT/VF). We hypothesized that prevention of ventricular arrhythmias by the β-blocker/sympatholytic agent bucindolol is influenced by genetic variation in adrenergic receptors. METHODS AND RESULTS Fro...

Cell development is regulated by a complex network of mRNA-encoded proteins and microRNAs, all funnelling onto the modulation of self-renewal or differentiation genes. How intragenic microRNAs and their host genes are transcriptionally coregulated and their functional relationships for the control of neural stem cells (NSCs) are poorly understood. We propose here the intragenic miR-326 and its ...

This comment is to show that Theorem3.3 of Dey and Chung (1991) (Multiparameter estimation intruncated power series distributions under the Stein's loss.emph{Commun. Statist.-Theory Meth.,} {bf 20}, 309-326) may giveus misleading results. Analytically and through simulation, weshow that the Theorem does not improve the given estimator.

cancer. N Engl J Med 326:653-657, 1992 (9) Kelly RB, Shank C: Adherence to screening flexible sigmoidoscopy in asymptomatic patients. Med Care 30:1029-1042, 1992 (10) Atkin WS, Morson BC, Cuzick J: Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. N Engl J Med 326:658—662, 1992 (//) Atkin WS, Cuzick J, Northover JMA, et al: Prevention of colorectal cancer by once-only...