In the title compound, C36H42O8, the dioxolane ring adopts a twist conformation; the two adjacent C atoms deviate alternately from the mean plane of other atoms by -0.287 (5) and 0.174 (5) Å. The cyclo-hexane, cyclo-hexa-diene and central cyclo-octane rings show chair, half-chair and boat-chair forms, respectively. As a result of the strained ring system, the tetra-subsituted olefin in the cycl...

Marine derived cyclo(Gly-l-Ser-l-Pro-l-Glu) was selected as a lead to evaluate antitumor-antibiotic activity. Histidine was chosen to replace the serine residue to form cyclo(Gly-l-His-l-Pro-l-Glu). Cyclic tetrapeptides (CtetPs) were then synthesized using a solution phase method, and subjected to antitumor and antibiotic assays. The benzyl group protected CtetPs derivatives, showed better acti...

The title tricyclic diene, C(24)H(22)Cl(2), is the product of thermal ring-opening of a corresponding basketane (penta-cyclo-[4.4.0.0(2,5).0(3,8).0(4,7)]deca-ne) derivative. The cyclo-butene ring is planar to within 0.0032 (12) Å and its geometry is normal. The two 4-chloro-phenyl groups are oriented in an approximately face-to-face conformation with a dihedral angle of 44.14 (6)° between them....

Sponge-associated fungi represent the single most prolific source of novel natural products from marine fungi. Cyclo (L-Trp-L-Phe) exhibits biological functions such as plant growth regulation, moderate cytotoxicity and thus has the application potential in pharmaceutical and agricultural biotechnologies. In this study, a fungal strain TS08 was isolated from sponge Holoxea sp. in the South Chin...

Starting from tris(trimethylsilyl)silane the novel 2-chloro-3,4-bis-tris(trimethylsilyl)silyl-cyclo-diphospha-diazenium-tetrachloridogallate salt (7) was prepared in a six step synthetic procedure including the synthesis of N-tris(trimethylsilyl)silyl-aminodichlorophosphine (4) and 1,3-dichloro-2,4-bis-tris(trimethylsilyl)silyl-cyclo-diphospha-diazane (5). All intermediate products along the re...

The mol-ecule of the title compound, C(16)H(21)BO(2), comprises a chiral fused tricyclic system containing five-membered (1,3,2-dioxaborolane), six-membered (cyclo-hexa-ne) and four-membered (cyclo-butane) rings. The 1,3,2-dioxaborolane ring is almost planar (r.m.s. deviation = 0.035 Å), and the syn H and Me substituents at this ring are in an eclipsed conformation. The cyclo-hexane and cyclo-b...

The title compound, C15H24O2 {systematic name: 1-[6-hy-droxy-7-(propan-2-yl)-4-methyl-idene-2,3,3a,4,5,6,7,7a-octa-hydro-1H-inden-1-yl]ethanone} was iso-la-ted from A. reticulata by column chromatography over silica gel by gradient solvent elution. The mol-ecule comprises a bi-cyclo-[4.3.0]nonane ring bearing acet-oxy, hy-droxy and isopropyl substituents, and an exocyclic double bond on the cyc...

4-[(2-Amino-4-phenylazo)-methyl]-cyclo hexane carboxylic acid, a new Azo (LH2) ligand, was synthesized by reaction of the diazonium salt trans-4-(amino-methyl) cyclo acid with 3-amino phenol. The azo ligand characterized micro elemental analysis (C.H.N.O.) and TGA as well spectroscopic techniques (UV-Vis, FTIR, 1H-NMR, LC-Mass). Atomic absorption, analysis, infrared, LC-Mass, TGA, UV-Vis spectr...

Eine Reihe gespannter aromatischer Makrozyklen basierend auf [n]Cyclo-2,7-(4,5,9,10-tetrahydro)pyrenylenen wurde an der K-Region Pyreneinheit mit Ethylenglykol-Gruppen funktionalisiert, um im Innenraum des Makrozyklus eine definierte Bindungstasche zu formen. Diese ist für den fünfgliedrigen besonders ausgeprägt, was einer Bindungskonstante von 8.0×104 m−1 zwischen dem Ether-dekorierten [5]Cycl...