The Center for Veterinary Medicine, U.S. Food and Drug Administration (FDA/CVM) has authority under the United States Code 21 under Section 514.80 to monitor for adverse experiences of approved animal products. Although veterinarians voluntarily report suspect drug-related events to manufacturers, firms that market FDA-approved animal products must report serious events to the FDA within 15 wor...

An important problem in statistics is to obtain information about the form of the population from which the sample is drawn. Goodness of fit test is employed to determine how well the observed sample data "fits" some proposed model. The standard goodness of fit statistics are inappropriate when the parameters of the hypothesized distribution are estimated from the data used for the test. In thi...

Clustering algorithms have evolved to handle more and more complex structures. However, the measures that allow to qualify the quality of such clustering partitions are rare and have been developed only for specific algorithms. In this work, we propose a new cluster validity measure (CVM) to quantify the clustering performance of hierarchical algorithms that handle overlapping clusters of any s...

Les autrices proposent un cadre d'analyse des effets genrés du COVID-19 sur les travailleurs de trois chaînes valeur mondiales (CVM): services externalisés, l'habillement et l'électronique. Elles distinguent ces selon qu'ils sont induits par la maladie ou mesures confinement, découlent l'offre demande. tiennent compte caractère multidimensionnel bien-être, l'imbrication sphères production repro...

Standard SVM training has O(m3) time and O(m2) space complexities, where m is the training set size. It is thus computationally infeasible on very large data sets. By observing that practical SVM implementations only approximate the optimal solution by an iterative strategy, we scale up kernel methods by exploiting such “approximateness” in this paper. We first show that many kernel methods can...

Folding of the triangular lattice in a discrete three-dimensional space is investigated numerically. Such "discrete folding" has come about through theoretical investigation, since Bowick and co-workers introduced it as a simplified model for the crumpling of the phantom polymerized membranes. So far, it has been analyzed with the hexagon approximation of the cluster variation method (CVM). How...

OBJECTIVE The aim of this study was to investigate the association between dental and skeletal maturity. STUDY DESIGN Digital panoramic radiographs and lateral skull cephalograms of 302 patients (134 boys and 168 girls, ranging from 8 to 16 years of age) were examined. Dental maturity was assessed by calcification stages of the mandibular canines, first and second premolars, and second molars...

The pervasiveness of complex communication services and the need for end-users to play a greater role in modeling communication services have resulted in the development of the Communication Modeling Language (CML). CML is a domain-specific modeling language that can be used to declaratively specify user-centric communication services. CML models are automatically realized using the Communicati...