background and aims. oral lichen planus is a relatively common chronic oral mucosal disease of unknown etiology. regarding numerous studies on the immunologic factors involved in the etiology of lichen planus, the present study evaluated the serum interleukin-17 (il-17) level in patients with erosive and non-erosive oral lichen planus. materials and methods. this descriptive analytical study in...

Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact. Since 2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence. The authors describe an exuberant case of secondary syphilis, presenting with annular and lichen planus-like lesions, as well as one mucocutaneous lesion. Physicians must be aware of syphilis in daily practice...

Lichen planus (LP) and lichen sclerosus (LS) are cutaneous-mucous diseases with uncertain epidemiology. Current data, which are likely to be underestimated, suggest a prevalence in the general population of 0.1-4% for cutaneous LP, 1.27-2.0% for oral LP, and 0.1-3.3% for LS. While etiology of lichen is still unknown, clinical and histological evidence show an (auto)immune pathogenesis. Associat...

Lichenoid drug eruptions can mimic idiopathic lichen planus and other dermatoses. The list of drugs that can cause them is long and growing steadily. Although cutaneous side effects of antipsychotics are rare, various cutaneous manifestations have been reported in association with olanzapine. We present the case of a patient who developed an atypical lichenoid eruption due to olanzapine. A revi...

STATEMENT OF PROBLEM Lichen planus is a chronic inflammatory immunologic-based disease involving skin and mucosa. This disease is generally divided into two categories: erosive and non-erosive. Many etiologic factors are deliberated regarding the disease; however, the disorders of immune system and the role of cytotoxic T-lymphocytes and monocytes are more highlighted. Zinc is an imperative ele...

lichen planus (lp) is a chronic mucocutaneous disease widely recognized in adults, but uncommon in children. the purpose of this paper is to report two cases of lp in children. the diagnosis was made based on clinical and histopathological findings. the treatment consisted of antifungal and multivitamin therapy. regression of lesions was observed. the patients are still under follow up. althoug...

Lichen planus (LP) is a common disorder in which auto-cytotoxic T lymphocytes trigger apoptosis of epithelial cells leading to chronic inflammation. Oral Lichen Planus (OLP) can be a source of severe morbidity and has a small potential to be malignant. The diagnosis of OLP can be made from the clinical features if they are sufficiently characterized, but biopsy is recommended to confirm the dia...

UNLABELLED Oral lichen planus is one of the most common dermatological diseases presenting in the oral cavity; the prevalence in the general population is 1% to 2%. Although relatively frequent, oral lichen planus is the target of much controversy, especially in relation to its potential for malignancy. AIM This study aimed to make clinical and histopathological considerations regarding oral ...

HLP: hypertrophic lichen planus LP: lichen planus PEH: pseudoepitheliomatous hyperplasia SCC: squamous cell carcinoma INTRODUCTION Hypertrophic lichen planus (HLP) and squamous cell carcinoma (SCC) share many clinical and histopathologic characteristics, making them difficult to distinguish. HLP may undergo malignant transformation, leading to the development of SCC within HLP. We present a cas...

Background: Oral Lichen Planus (OLP) is a chronic autoimmune disease that could be considered as a potential premalignant status. Objective: To evaluate the miRNA-146a and miRNA-155 expression levels in patients with oral Lichen planus lesions compared to healthy subjects with normal oral mucosa. Methods: Forty patients with oral lichen planus and 18 healthy age and gender-matched controls were...