نتایج جستجو برای: cutaneous basophil hypersensitivity

تعداد نتایج: 91842  

Journal: :Cancer research 1976
J A Roth H K Slocum M A Pellegrino E C Holmes R A Reisfeld

Soluble extracts of melanoma specimens were prepared by 3 M KCl extraction. Delayed cutaneous hypersensitivity reactions to these antigens were noted in 25 of 39 melanoma patients and 7 of 30 patients with other neoplasms. Only 4 of 34 melanoma patients reacted to an extract of autologous muscle. Maximum reactivity to these antigens occurred at 24 hr and was demonstrated histologically by skin ...

Journal: :Postgraduate medical journal 1979
D Q Borsey D N Malone

A case is described of a patient who developed local cutaneous hypersensitivity soon after commencing treatment with monocomponent insulins (MCI). This appears to be the first record of such a case.

Journal: :Haematologica 2005
Albert Haddad Odile Marek Maria Elena Noguerra Jacqueline Rivet Celeste Lebbé Pauline Brice

T-cell lymphoproliferation are less frequent than B-cell and have some particular clinical features. We present a patient presenting with a reversible cutaneous and blood T-lymphocyte clonal expansion this case may be closed to the drug hypersensitivity syndrome.

Journal: :Infection and immunity 1971
I R Tizard M A Soltys

Animals infected with strains of Trypanosoma brucei and T. rhodesiense exhibited cutaneous hypersensitivity to intradermal administration of antigen. This reactivity was of two types, an Arthus-type, antibody-mediated reaction which reached maximum intensity 4 hr after injection and a delayed-type, cell-mediated reaction which reached maximum intensity 24 hr after injection. This delayed-type h...

Journal: :Blood 2007
Kazushige Obata Kaori Mukai Yusuke Tsujimura Kenji Ishiwata Yohei Kawano Yoshiyuki Minegishi Naohiro Watanabe Hajime Karasuyama

Basophils represent less than 1% of peripheral blood leukocytes and have often been considered as minor and possibly redundant circulating mast cells. The recent finding that basophils readily generate large quantities of T helper 2 (Th2) cytokines such as IL-4 provided new insights into the possible role of basophils in allergic disorders and immunity to pathogens. However, in-depth studies on...

Journal: :Journal of Medical Case Reports 2008
Sylvia Lehmann Hagen Ott

INTRODUCTION Immediate-type hypersensitivity to glucocorticosteroids is rare but well known among allergists. Surprisingly, very few reports of glucocorticosteroid hypersensitivity in children exist although glucocorticosteroid treatment is particularly common in this age group. CASE PRESENTATION We report the case of a 2-year-old boy who developed generalized urticaria, facial angio-oedema, ...

Journal: :Allergy 2011
Marek L Kowalski J S Makowska M Blanca S Bavbek G Bochenek J Bousquet P Bousquet G Celik P Demoly E R Gomes E Niżankowska-Mogilnicka A Romano M Sanchez-Borges M Sanz M J Torres A De Weck A Szczeklik K Brockow

Nonsteroidal anti-inflammatory drugs (NSAIDs) are responsible for 21-25% of reported adverse drug events which include immunological and nonimmunological hypersensitivity reactions. This study presents up-to-date information on pathomechanisms, clinical spectrum, diagnostic tools and management of hypersensitivity reactions to NSAIDs. Clinically, NSAID hypersensitivity is particularly manifeste...

2004
TS Cheng KM Ho KK Jong

Cutaneous tuberculosis (CT) can be classified as true cutaneous tuberculosis and tuberculids which is regarded as a hypersensitivity reaction to Mycobacterium tuberculosis in patients with a high degree of tuberculin sensitivity. Papulonecrotic tuberculid (PNT) is a form of tuberculid. It is an uncommon manifestation even in areas with high prevalence of tuberculosis. The following is a case re...

2017
Abimbola Adike Vaishnavi Boppana Dora Lam-Himlin Melissa Stanton Steven Nelson Kevin C Ruff

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a rare but potentially life-threatening cutaneous hypersensitivity reaction characterized by extensive mucocutaneous eruption, fever, hematologic abnormalities, and extensive organ involvement. Here, we present a case of a young woman with DRESS syndrome following exposure to vancomycin with renal, cutaneous, and gastrointestinal ...

Journal: :Cancer research 1965
S E Blomgren W H Wolberg W A Kisken

although recently paradoxical potentiation of antibody titers has been reported (11, 14). Cancer chemotherapists have been concerned for many years that the drugs used in treating cancer might suppress any host immunity to the tumor and actually hasten rather than retard its spread. It was for this reason that the present study was under taken. Briefly, the experimental design consisted of asse...

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