A rapid, simple, selective and precise UVVisible Spectrophotometric method has been developed for the determination of Curcumin in bulk forms and solid dosage formulations. The spectrophotometric detection was carried out at an absorption maximum of 421 nm using methanol as solvent. The method was validated for specificity, linearity, accuracy, precision, robustness and ruggedness. The detector...

Fish oils have many dietary benefits, but due to their strong odors and rapid deterioration, their application in food formulations is limited. For these reasons, nano-liposome was used to nano-encapsulate fish oil in this study and encapsulated fish oil was utilized in fortifying yogurt. Physicochemical properties of produced yogurt including pH, acidity, syneresis, fatty acid composition, per...

The goal of this investigation was to determine the effectiveness hydrophilic polymers in preparing a solid dispersion enhance solubility and dissolution poorly water-soluble drugs, such as curcumin. In order prepare dispersion, curcumin uniformly distributed polymeric matrix polyethylene glycol (PEG 6000), hydroxypropyl methyl cellulose (HPMC E5), polyvinyl pyrrolidine (PVP K30), bovine serum ...

Trichinella spiralis can cause systemic inflammatory manifestations all over the body beforehabituating their destination in striated muscles. Its new borne larvae (NBL) most dangerousphase go via bloodstream of different organs during migration.This study explored anti-inflammatory, antioxidant and anti-apoptotic effects Curcumin(Cur) Curcumin nanoparticles (Cur-Nano) on pathological changes o...

The aim of this article was to study the trans-epithelial absorption to reach the blood and to target the brain by axonal transport using nasal formulations with nanonized meloxicam (nano MEL spray) and its salt form known as meloxicam potassium monohydrate (MELP spray). The physicochemical properties and the mucoadhesivity of nasal formulations were controlled. In vitro and in vivo studies wer...

In part I of this review we assessed nanoscience-related definitions as applied to pharmaceuticals and we discussed all 43 currently approved drug formulations, which are widely publicized as nanopharmaceuticals or nanomedicines. In continuation, here we review the currently ongoing clinical trials within the broad field of nanomedicine. Confining the definition of nanopharmaceuticals to therap...