Tuberkulosis (TB) merupakan penyakit infeksi yang masih menjadi permasalahan global. Kasus TB di provinsi Bengkulu sebanyak 17.419 jiwa dan 334 Kota Bengkulu. Untuk mengatasi masalah ini, maka keluarga perlu diberdayakan sebagai pengawas menelan obat (PMO). Tujuannya adalah terbangunnya model pemberdayaan PMO berpengaruh terhadap kemandirian salam merawat pasien TB. Desain penelitian observasi ...

Daratumumab is a human CD38-directed monoclonal antibody approved in the United States as monotherapy for patients with multiple myeloma (MM) who have received ≥3 prior lines of therapy (LOTs), including a proteasome inhibitor (PI) and an immunomodulatory agent (IMiD) or who are double refractory to a PI and an IMiD, and in combination with lenalidomide/dexamethasone or bortezomib/dexamethasone...

Purpose The low-income subsidy (LIS) substantially lowers out-of-pocket costs for qualifying Medicare Part D beneficiaries who receive orally administered chemotherapy. We examined the association of LIS with the use of novel oral immunomodulatory drugs (IMiDs; lenalidomide and thalidomide) among beneficiaries with myeloma, who can receive either orally administered or parenteral (bortezomib-ba...

INTRODUCTION Latent tuberculosis infection (LTBI) is detected with the tuberculin skin test (TST) before anti-TNF therapy. We aimed to investigate in vitro blood assays with TB-specific antigens (CFP-10, ESAT-6), in immune-mediated inflammatory diseases (IMID) for LTBI screening. PATIENTS AND METHODS Sixty-eight IMID patients with (n = 35) or without (n = 33) LTBI according to clinico-radiogr...

Pulsed Magneto-Oscillation (PMO) is a newly developed and effective homogenization technique, has been successfully applied in rectangular continuous casting, but its processing parameters stability round billet casting have not investigated. In this paper, the effects of PMO on solidification structure macrosegregation Φ 178 mm billets for low carbon alloy steel were studied by industrial expe...

The application of a novel palladium containing ionic liquid based periodic mesoporous organosilica (Pd@PMO-IL) catalyst in the aerobic oxidation of primary and secondary alcohols under molecular oxygen and air atmospheres is investigated. It was found that the catalyst is quite effective for the selective oxidation of several activated and non-activated alcoholic substrates. The catalyst syste...

BACKGROUND Sub optimal levels of compliance and persistence with bisphosphonates are potentially compromising the reduction of post menopausal osteoporotic (PMO) fracture risk. METHODS A structured literature search (1990-2006) was performed to identify primary research studies evaluating the relationship between compliance and persistence with bisphosphonates and post menopausal osteoporotic...

Application of e-business concepts and models can be successful, but anecdotal evidence has indicated numerous failures. In this paper we use a framework (the I-Frame) to analyze a bestpractice implementation of a buyer-owned electronic trading exchange at Komatsu America Corp. – Peoria Manufacturing Operations (KAC-PMO). The I-Frame is derived from five existing models in the literature and de...

BACKGROUND Middle-aged women experience various health-related problems. The aim of this study was to evaluate the impacts of menopause status and hormone intervention on women's health. METHODS In an ongoing, population-based study, 4943 women, born 1935 to 1945 and living in the Lund area of Southern Sweden, were included in this analysis. They completed a generic questionnaire pertaining t...