It is suggested to screen for bone metastases with bone scans and monitor for lymph node and visceral metastases/progression with imaging of the abdomen and chest. Patients with a rapid PSA doubling time (PSADT) (<8 months) are at risk for developing earlier metastases. Imaging in these patients should be performed every 3 to 6 months. Patients with slower PSA DT (>12 months) should be screened...

This experiment was designed to determine whether dietary hemoglobin (Hgb) iron (Fe) could 0271-5317/$ – see fro doi:10.1016/j.nutres.2 4 Corresponding a E-mail address: p sustain normal Fe status in growing rats adequate or deficient in copper (Cu). Forty-eight weanling rats were divided into 3 groups, each consisting of 16 animals. One group was fed a diet containing 40 mg Fe/kg as ferrous su...

The steady-state behaviour of isolated mammalian cytochrome c oxidase was examined by increasing the rate of reduction of cytochrome c. Under these conditions the enzyme's 605 (haem a), 655 (haem a3/CuB) and 830 (CuA) nm spectral features behaved as if they were at near equilibrium with cytochrome c (550 nm). This has implications for non-invasive tissue measurements using visible (550, 605 and...

Overcoming obstacles to prosthetic fittings requires frequent tryouts of sockets and components. Repetitions interventions are upsetting for users place substantial economic burden on healthcare systems. Encouraging care innovations capable alleviating clinical financial shortcomings socket-based solutions is essential. Nonetheless, evidence socio-economic benefits an innovation required facili...

OBJECTIVES To evaluate the cost effectiveness, cost utility and cost benefit of a workplace intervention compared with usual care for sick-listed employees with distress. METHODS An economic evaluation was conducted alongside a randomised controlled trial. Employees with distress and who were sick-listed for 2-8 weeks were randomised to a workplace intervention (n=73) or to usual care (n=72)....

OBJECTIVE To analyze the cost/benefit (CBA), cost/effectiveness (CEA) and cost/utility (CUA) of colorectal cancer (CC) screening through the detection of fecal occult blood (FOB). METHODS A retrospective 10-year study was carried out in primary care hospitals to observe the evolution of CC in the study zone; subsequently, CC screening with FOB detection was done, and the entire population age...

Using a mutant pyrrolysyl-tRNA synthetase-tRNA(Pyl)(CUA) pair, 3-formyl-phenylalanine is genetically incorporated into proteins at amber mutation sites in Escherichia coli. This non-canonical amino acid readily reacts with hydroxylamine dyes, leading to rapid and site-selective protein labelling.