نتایج جستجو برای: cryo

تعداد نتایج: 7054  

Journal: :Atmospheric Chemistry and Physics 2021

Abstract. Cirrus clouds composed of small ice crystals are often the first solid matter encountered by sunlight as it streams into Earth's atmosphere. A broad array recent research has emphasized that photon particle scattering calculations very sensitive to morphology, complexity, and surface roughness. Uncertain variations in these parameters have major implications for successfully parameter...

Journal: :Applied and Computational Harmonic Analysis 2023

We study a class of orbit recovery problems in which we observe independent copies an unknown element $\mathbb{R}^p$, each linearly acted upon by random some group (such as $\mathbb{Z}/p$ or $\mathrm{SO}(3)$) and then corrupted additive Gaussian noise. prove matching upper lower bounds on the number samples required to approximately recover this with high probability. These bounds, based quanti...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Alberto Bartesaghi Doreen Matthies Soojay Banerjee Alan Merk Sriram Subramaniam

We report the solution structure of Escherichia coli β-galactosidase (∼465 kDa), solved at ∼3.2-Å resolution by using single-particle cryo-electron microscopy (cryo-EM). Densities for most side chains, including those of residues in the active site, and a catalytic Mg(2+) ion can be discerned in the map obtained by cryo-EM. The atomic model derived from our cryo-EM analysis closely matches the ...

2010
Audrey Lasalle Christian Guizard Sylvain Deville Fabrice Rossignol Pierre Carles

We illustrate in this paper the interest of cryo-field-emission gun scanning electron microscopy (cryo-FEGSEM) to investigate the stability of alumina suspensions. The stability is investigated through viscosity, zeta potential, total organic carbon measurements, and cryo-FEGSEM observations. We focus on two examples: the effect of the quantity of ammonium polyacrylate as dispersant and the eff...

Journal: :Journal of structural biology 2016
Feng Wang Huichao Gong Gaochao liu Meijing Li Chuangye Yan Tian Xia Xueming Li Jianyang Zeng

Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM). Here we report a deep learning framework, called DeepPicker, to address this problem and fill the current gaps toward a fully automated cryo-EM pipeline. DeepPicker employs a novel cr...

2016
Jun Zhu Yan Zhang Aili Zhang Kun He Ping Liu Lisa X. Xu

Achieving control of metastatic disease is a long-sought goal in cancer therapy. Treatments that encourage a patient's own immune system are bringing new hopes in reaching such a goal. In clinic, local hyperthermia and cryoablation have been explored to induce anti-tumor immune responses against tumors. We have also developed a novel therapeutic modality of cryo-thermal treatment by alternating...

2012
Daniel A Jones Ross J Hunter Redha Boubertakh Louisa Malcolme-Lawes Prapa Kanagaratnam Nicholas S Peters Christoph Juli Victoria Baker Mark Earley Simon Sporton Ceri Davies Mark Westwood Richard J Schilling Steffen E Petersen

Methods Consecutive patients with paroxysmal AF in a randomised study comparing pulmonary vein isolation by wide area circumferential radiofrequency ablation (WACA) to ostial ablation with a cryo-balloon (CRYO) underwent CMR late gadolinium enhancement (LGE) imaging preand 3 months post ablation. Imaging was anonymized for blinded analysis of (1) LGE images, and (2) a 3D fusion image with LGE p...

Journal: :Molecules 2018
Lin Chen Jing He Salim Sazzed Rayshawn Walker

Cryo-electron microscopy (cryo-EM) is a structure determination method for large molecular complexes. As more and more atomic structures are determined using this technique, it is becoming possible to perform statistical characterization of side-chain conformations. Two data sets were involved to characterize block lengths for each of the 18 types of amino acids. One set contains 9131 structure...

2013
Tanja Kurzendorfer Alexander Brost Carolin Jakob Philip W. Mewes Felix Bourier Martin Koch Klaus Kurzidim Joachim Hornegger Norbert Strobel

Minimally invasive catheter ablation has become the preferred treatment option for atrial fibrillation. Although the standard ablation procedure involves ablation points set by radio-frequency catheters, cryo-balloon catheters have even been reported to be more advantageous in certain cases. As electro-anatomical mapping systems do not support cryo-balloon ablation procedures, X-ray guidance is...

2017
James Winearls Martin Wullschleger Elizabeth Wake Catherine Hurn Jeremy Furyk Glenn Ryan Melita Trout James Walsham Anthony Holley Jeremy Cohen Megan Shuttleworth Wayne Dyer Gerben Keijzers John F Fraser Jeffrey Presneill Don Campbell

BACKGROUND Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen replacement is recommended by several international trauma guidelines using either fibrinogen concentrate (FC) or cryoprecipitate (Cryo). There is limited evidence to support one product over the other with widespread geograp...

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