نتایج جستجو برای: crossmatch
تعداد نتایج: 426 فیلتر نتایج به سال:
Putative antibody-mediated rejection (AMR) in HLA-identical sibling transplantation has rarely been reported and occurred before routine calcineurin inhibitor use. A 29-year-old male developed allograft dysfunction following an HLA-identical renal transplant from his sibling. A pretransplant panel-reactive antibody (PRA) was elevated, pre-transplant crossmatch was negative and no donor-specific...
SENSITI ZA TION of potential transplant recipients by formation of Iymphocytotoxic antibodies can be a result of prior blood transfusions, pregnancy. or failed allograft transplantation. While the presence of preformed anti-HlA-A and -B Iymphocytotoxic antibodies does not appear to influence the survival of liver allografts; this has been a contraindication in renal transplantation because of t...
BACKGROUND We previously reported that in patients possessing human leukocyte antigen (HLA)-DQ-directed antibodies, the target molecule may include the patient's own DQβ chain if it is paired with non-self-DQα chain, thus forming a different DQ target. Herein, we sought to assess the breadth of this phenomenon. METHODS Serum samples from 104 patients awaiting kidney transplantation, known to ...
PROBLEM There is substantial data that support the efficacy of paternal leukocyte immunization (PLI) for the treatment of alloimmune mediated miscarriage; however, there is confusion regarding the laboratory test that should be performed to determine levels of maternal anti-paternal leukocyte antibodies (MAPLA). METHOD Popular methodologies employed include: 1) microcytotoxicity (MCX), 2) mix...
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