نتایج جستجو برای: cross over study

تعداد نتایج: 4958685  

2017
Saravanapriah Nadarajan Talley J Lambert Elisabeth Altendorfer Jinmin Gao Michael D Blower Jennifer C Waters Monica P Colaiácovo

The synaptonemal complex (SC) is an ultrastructurally conserved proteinaceous structure that holds homologous chromosomes together and is required for the stabilization of pairing interactions and the completion of crossover (CO) formation between homologs during meiosis I. Here, we identify a novel role for a central region component of the SC, SYP-4, in negatively regulating formation of reco...

Journal: :Alcohol and alcoholism 2007
Srdjan Djurovic Knut Erik Berge Bård Birkenes Øivind Braaten Lars Retterstøl

AIMS It has been reported that alcohol has multiple effects on appetite. To elucidate potential mechanisms we measured the levels of plasma leptin and the vasoactive factors after red wine intake. METHODS We conducted a randomized crossover trial to study the effect of red wine on the levels of leptin, TNF-alpha, TGF- beta(1), IL-6, ICAM-1, and VCAM-1 in healthy, non-smoking individuals. The ...

Journal: :PLoS Genetics 2007
Jan Drouaud Raphaël Mercier Liudmila Chelysheva Aurélie Bérard Matthieu Falque Olivier Martin Vanessa Zanni Dominique Brunel Christine Mézard

In many species, sex-related differences in crossover (CO) rates have been described at chromosomal and regional levels. In this study, we determined the CO distribution along the entire Arabidopsis thaliana Chromosome 4 (18 Mb) in male and female meiosis, using high density genetic maps built on large backcross populations (44 markers, >1,300 plants). We observed dramatic differences between m...

Journal: :BMC Musculoskeletal Disorders 2009
Jill Thiele Rachel Nimmo Wendy Rowell Stephen Quinn Graeme Jones

BACKGROUND To compare the effectiveness of a custom-made leather wrist splint (LS) with a commercially available fabric splint (FS) in adults with chronic wrist pain. METHODS Participants (N = 25, mean age = 54) were randomly assigned to treatment order in a 2-phase crossover trial. Splints were worn for 2 weeks, separated by a one-week washout period. Outcomes were assessed at baseline and a...

Journal: :The Journal of Cell Biology 2008
Richard Robinson

A pair of adhesion receptors work together to fi ne-tune suppression of RhoA and promote membrane protrusion, say Bass et al. During cell migration, the actin cyto-skeleton regulator, RhoA, must be alternately inhibited (to allow the leading membrane edge to protrude) and reactivated (to pull up the trailing end of the cell from behind). Inhibition occurs when a receptor called α5β1 integrin, w...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Barbara Arbeithuber Andrea J Betancourt Thomas Ebner Irene Tiemann-Boege

Meiosis is a potentially important source of germline mutations, as sites of meiotic recombination experience recurrent double-strand breaks (DSBs). However, evidence for a local mutagenic effect of recombination from population sequence data has been equivocal, likely because mutation is only one of several forces shaping sequence variation. By sequencing large numbers of single crossover mole...

2016
Rachael Frost Doreen McClurg Marian Brady Brian Williams

BACKGROUND Diaries are the most commonly used adherence measurement method in home-based rehabilitation trials, yet their completion and validity varies widely between trials. We aimed to: (1) generate theory to explain this variation, (2) create an optimised diary and (3) evaluate the optimised diary's validity. METHODS Stage 1. DEVELOPMENT using a multiple case study approach, we collecte...

2016
Manon Ragonnet-Cronin Samantha J. Lycett Emma B. Hodcroft Stéphane Hué Esther Fearnhill Alison E. Brown Valerie Delpech David Dunn Andrew J. Leigh Brown

BACKGROUND The United Kingdom human immunodeficiency virus (HIV) epidemic was historically dominated by HIV subtype B transmission among men who have sex with men (MSM). Now 50% of diagnoses and prevalent infections are among heterosexual individuals and mainly involve non-B subtypes. Between 2002 and 2010, the prevalence of non-B diagnoses among MSM increased from 5.4% to 17%, and this study f...

Journal: :Gut 1993
C Ferri E Marzo G Longombardo L La Civita F Lombardini D Giuggioli R Vanacore A M Liberati A Mazzoni F Greco

To confirm the positive results of a preliminary trial, 26 patients with mixed cryoglobulinaemia were enrolled in a controlled, randomised, crossover trial with interferon alfa-2b. A significant improvement was seen in the purpura score and alanine aminotransferase activities during six months' treatment, and was associated with a significant decrease in cryocrit and a returning to normal of th...

Journal: :Appetite 2003
Phillip N Ritchey Robert A Frank Ulla-Kaisa Hursti Hely Tuorila

The food neophobia scale [FNS; Appetite 19 (1992) 105] has been used to assess willingness to try new foods in studies conducted around the world. Although it is tempting to compare FNS scores across these studies, appropriate psychometric analyses are required to validate the scale and allow cross-cultural comparisons. These analyses were pursued in the current study using confirmatory factor ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید